Adoption of Cross-Layer based techniques in Wireless Sensor Network (WSN) has been reported to be an efficient solution towards improving energy efficiency, scheduling related problems among the resource-limited sensor nodes. The existing approaches are reviewed to ensure that there exists further scope for the improvement and enhancement in terms of resolving the issues associated with even faster interaction among the layers of the conventional protocol stack for catering up and facilitating the demands of faster response time in real-time applications. Therefore, Cross Layer Interactive Framework (CLIF) a novel and advanced approach is proposed for essentially sustaining symmetry between the crucial performance parameters like data delivery and energy efficiency for a given dynamic communication circumstances in WSN. In addition, to this message prioritization is incorporated in CLIF for processing those messages with high degree of significance. Predominantly CLIF can be used for the diverse time critical and mission critical IoT applications. The results demonstrate that the proposed CLIF scheme offers better energy efficiency and enhanced data delivery services in WSN when compared with the existing cross-layer approaches.