“…Impaired perceptions of QoL affect indigestion and pain as well. These factors can lead to a feeling of helplessness, despair, sleep disturbances, adverse anti-tumor immune response, earlier relapse, worsening of concomitant disease and lower overall survival rates [1]. The long-term treatment process is associated with the accumulation of various disease states and difficulties such as appearance changes, infertility, sexual dysfunction, hair loss, fatigue, nausea, vomiting, pain, infections, decreased blood levels and others [2].…”