Integration of Bioinformatics in Bioremediation

Khan, Nida Tabassum

doi:10.4172/2090-4924.1000130

Cited by 3 publications

(1 citation statement)

References 54 publications

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“…Different bioinformatic approaches can be effectively used in tracing numerous biodegradation pathways, physiochemical analysis of toxins, prediction of thee levels of toxicity, genomic and proteomic approaches to enzyme system of microbes, prediction of path of degradation , and reaction kinetics for remediation of contaminants. So Bioinformatics hold prospective purpose for the development of phytoremediation technology [16] . Bioinformatics requires the study of plant genomics, proteomics, systems biology, computational biology, phylogenetic trees, data mining and application of major bioinformatics tools for determining the structures and biodegradative pathways of xenobiotic compounds [4] .…”

Section: Practical Application Of Omics In Phytoremediation Technology Has Been Represented In the Tablementioning

confidence: 99%

Proteomics and Bioinformatics as Novel Tools in Phytoremediation Technology- An Overview

Mohanty

2021

j. of bot. res.

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Biotechnology plays an important role in mitigation of various pollution in a cost effective manner by using the complex chemistry of living organisms, various cell manipulations and their approaches for environmental cleanup along with environmental sustainability. One such technology is phytoremediation technology or green technology which has emerged and evolved as a novel tool for remediation of toxic contaminants from environment. Plants with its diverse range show a remarkable range of their phytoremediation potentiality for establishing a sustainable environment. There is a huge exploitation of natural resources through expanded industrialization, urbanization, modern agricultural development, energy generation to fulfill the never-ending human desires and need. This disturbs the balance in nature where we reside and leads to progressive deterioration of the environment. There are several biotechnological advances which are employed for combating both the biotic and abiotic stress problems caused due to toxic contaminants in the environment. Various biotechnological interventions such as bioinformatics, proteomics, genomics, metallomics and metabolomics play a crucial role and open new avenue in this context. This omics approach is now integrated with bioinformatics to serve as a novel tool in phytoremediation technology. This smart technology provides insights into the complex behavior of enzymes, proteins and metabolites action and their biochemical pathways for degradation of wastes. This leads towards deriving a sustainable solution for environmental pollution.

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Section: Practical Application Of Omics In Phytoremediation Technology Has Been Represented In the Tablementioning

confidence: 99%

Proteomics and Bioinformatics as Novel Tools in Phytoremediation Technology- An Overview

Mohanty

2021

j. of bot. res.

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Omics approaches for elucidating molecular mechanisms of microbial bioremediation

Rawat

Rangarajan

2019

Smart Bioremediation Technologies

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Comparative Pan- and Phylo-Genomic Analysis of Ideonella and Thermobifida Strains: Dissemination of Biodegradation Potential and Genomic Divergence

Jayapalan,

Michealsamy

2024

Preprint

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Ideonella and Thermobifida were the most promising bacterial candidates for degrading plastic polymers. A comparative pan- and phylogenomic analysis of 33 Ideonella and Thermobifida strains was done to determine their plastic degradation potential, niche adaptation and speciation. The BPGA results revealed that the greater number of accessory genes in the strains indicated phenotypic plasticity. Phylogenetic diversity among the strains was inferred using core and pan genomes. The functional roles of the core and adaptive-associated genomes were scrutinized by pathway enrichment analyses. KEGG annotation revealed that the majority of the genes were associated with the metabolism of amino acids and carbohydrates. The detailed COG analysis revealed that approximately 40% of the pan genes performed metabolic functions. The unique gene pool consisted of genes chiefly involved in "general function prediction" and "amino acid transport and metabolism". The results of the present study revealed that these strains could assist in agronomic applications in the future since they devour N- compounds. The rational selection of strains of Ideonella is far more effective at depolymerizing plastics than that of Thermobifida. A greater number of unique genes, 1701 and 692, were identified for Ideonella sakaiensis 201-F6 and Thermobifida alba DSM-43795, respectively. Furthermore, we examined the singletons involved in xenobiotic catabolism. The unique singleton data were used to construct a supertree. To characterize the conserved patterns, we used SMART and MEME to identify domain and transmembrane regions in the unique protein sequences. Therefore, our study unravelled the genomic insights into the ecology-driven speciation of Ideonella and Thermobifida.

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Integration of Bioinformatics in Bioremediation

Cited by 3 publications

References 54 publications

Proteomics and Bioinformatics as Novel Tools in Phytoremediation Technology- An Overview

Proteomics and Bioinformatics as Novel Tools in Phytoremediation Technology- An Overview

Omics approaches for elucidating molecular mechanisms of microbial bioremediation

Comparative Pan- and Phylo-Genomic Analysis of Ideonella and Thermobifida Strains: Dissemination of Biodegradation Potential and Genomic Divergence

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