2019
DOI: 10.3390/mi10090613
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Integration of Horizontal and Vertical Microfluidic Modules for Core-Shell Droplet Generation and Chemical Application

Abstract: This paper presents a method for utilizing three-dimensional microfluidic channels fully to realize multiple functions in a single device. The final device structure was achieved by combining three independent modules that consisted of horizontal and vertical channels. The device allowed for the one-step generation of water-in-oil-in-water droplets without the need for partial treatment of the polydimethylsiloxane channel surface using separate modules for generating water-in-oil droplets on the horizontal pla… Show more

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Cited by 5 publications
(4 citation statements)
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“…Moreover, microfluidic 3D mixing is an emerging technology, and only a few designs have been reported in the literature [61]. The other three-dimensional configurations available in the literature comprise a 3D co-flow microfluidic device for synthesizing polymer particles [72], a 3D modular microfluidic platform for core-shell droplet generation [73], and a star-shaped 3D structure with multiple inlets for producing smaller droplets than conventional microfluidic devices [74].…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, microfluidic 3D mixing is an emerging technology, and only a few designs have been reported in the literature [61]. The other three-dimensional configurations available in the literature comprise a 3D co-flow microfluidic device for synthesizing polymer particles [72], a 3D modular microfluidic platform for core-shell droplet generation [73], and a star-shaped 3D structure with multiple inlets for producing smaller droplets than conventional microfluidic devices [74].…”
Section: Discussionmentioning
confidence: 99%
“…Yoon et al [ 85 ] have proposed using three independent modules to create a complex 3D microfluidic platform ( Figure 25 ). The final device combines the modules in such a manner that channels are placed both horizontally and vertically.…”
Section: Geometriesmentioning
confidence: 99%
“…In this respect, numerous studies have focused on fabricating microfluidic devices, performing numerical simulations, analyzing fluid movement, and testing the developed microchips in experimental syntheses. Researchers worldwide managed to exploit the advantages of microfluidic technology for generating microdroplets [ 44 , 53 , 59 , 72 , 80 , 85 , 86 , 87 , 88 ], porous films [ 45 ], double emulsion droplets [ 55 ], nanofibers [ 69 ], microcapsules [ 82 , 83 ], and micro- [ 32 , 56 , 57 , 58 , 70 , 77 , 82 ] and nanoparticles of various compositions, sizes, shapes and morphologies [ 6 , 42 , 50 , 52 , 54 , 60 , 61 , 65 , 66 , 68 , 74 , 76 , 78 , 84 ].…”
Section: Geometriesmentioning
confidence: 99%
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