2021
DOI: 10.1101/2021.03.21.436352
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Integrative genome-scale metabolic modeling reveals versatile metabolic strategies for methane utilization inMethylomicrobium albumBG8

Abstract: Methylomicrobium album BG8 is an aerobic methanotrophic bacterium that can mitigate environmental methane emission, and is a promising microbial cell factory for the conversion of methane to value-added chemicals. However, the lack of a genome-scale metabolic model (GEM) of M. album BG8 has hindered the development of systems biology and metabolic engineering of this methanotroph. To fill this gap, a high-quality GEM was constructed to facilitate a system-level understanding on the biochemistry of M. album BG8… Show more

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