1993
DOI: 10.1177/1045389x9300400402
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Intelligent Orthopaedic Materials

Abstract: In the use of implants in orthopaedic surgery, the critical reactions occur at the interface between the implant and the bone. The physical discontinuity between the implant and the bone results from the nature of the biomaterial and affects the mechanism of stress transfer. If the material is designed to minimise this discontinuity, there is the possibility to introduce control or adaptive processes and thus to develop the use of intelligent materials. This article examines this in terms of fracture fixation.… Show more

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Cited by 19 publications
(9 citation statements)
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“…In fact, many naturally occurring portions in animals and plants are provided with such function [2][3][4][5][6]. In the case of healing of a skin wound, for example, the defect is temporarily plugged with a fibrin clot, which is infiltrated by inflammatory cells, fibroblasts, and a dense capillary plexus of new granulation tissue.…”
Section: Introductionmentioning
confidence: 99%
“…In fact, many naturally occurring portions in animals and plants are provided with such function [2][3][4][5][6]. In the case of healing of a skin wound, for example, the defect is temporarily plugged with a fibrin clot, which is infiltrated by inflammatory cells, fibroblasts, and a dense capillary plexus of new granulation tissue.…”
Section: Introductionmentioning
confidence: 99%
“…These qualities are usually attributed to two key properties: ability to induce formation of an apatite layer on material surfaces in physiological conditions and ability to promote bone cells anchorage, attachment, spreading, growth, and differentation. [4][5][6][7][8] It is widely accepted that surface chemical structure exerts a significant influence over these two events. 9 Among the techniques available to turn polymeric biomaterials with limited or no tendency to mineralize into mineralizing ones, grafting of phosphate groups has been reported as a successful procedure.…”
Section: Introductionmentioning
confidence: 99%
“…Because damage deep within a material is particularly difficult to identify and repair, materials that have self-healing properties are desirable. In fact, there are many examples of self-healing materials in biology (Trask, 2007;Hastings & Mahmud, 1993;Martin, 1997;Albert & Wong, 1991). For example, in the case of a skin wound, the defect is temporarily plugged with a fibrin clot, which is infiltrated by inflammatory cells, fibroblasts, and a dense capillary plexus of new granular tissue.…”
Section: Introductionmentioning
confidence: 99%