2011
DOI: 10.1016/s2222-1808(11)60016-9
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Intense and exhaustive exercise induce oxidative stress in skeletal muscle

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Cited by 52 publications
(40 citation statements)
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“…It was evident that the groups treated with PMIMBP exerted a greater increase in SOD and GSH levels when compared to groups treated with MIMBP. The elevated levels of MDA i.e., enhanced lipid peroxidation in the gastrocnemius muscle of exercised control group rats, indicate oxidative damage to the tissue 1, 56. Furthermore, the increased NO levels in the muscle tissues are suggestive of stressed conditions 22 .…”
Section: Discussionmentioning
confidence: 99%
“…It was evident that the groups treated with PMIMBP exerted a greater increase in SOD and GSH levels when compared to groups treated with MIMBP. The elevated levels of MDA i.e., enhanced lipid peroxidation in the gastrocnemius muscle of exercised control group rats, indicate oxidative damage to the tissue 1, 56. Furthermore, the increased NO levels in the muscle tissues are suggestive of stressed conditions 22 .…”
Section: Discussionmentioning
confidence: 99%
“…The results from human and animal studies suggested that increased metabolic activity lead to significant changes in body biomolecules and oxidative systems (21). Exercise-induced oxidative damage in tissues has been shown to damage cellular membranes, induce cellular swelling, reduce cell membrane flow, maintain the ionic gradient, and cause tissue inflammation, DNA damage, and protein changes (22). The increase in MDA level has been reported to impair the metabolism, integrity and performance of muscle cells (22).…”
Section: Discussionmentioning
confidence: 99%
“…Exercise-induced oxidative damage in tissues has been shown to damage cellular membranes, induce cellular swelling, reduce cell membrane flow, maintain the ionic gradient, and cause tissue inflammation, DNA damage, and protein changes (22). The increase in MDA level has been reported to impair the metabolism, integrity and performance of muscle cells (22). It has been suggested that a decrease in the level of lipid peroxidation associated with regular exercise may be due to the increased level of antioxidant capacity (23).…”
Section: Discussionmentioning
confidence: 99%
“…The citric acid content in the sperm suspension of the seed extract fed rats revealed a significant decrement indicating the reduced oxidative metabolism. Citric acid level in the sperm suspension forms the index towards the level of oxidative metabolism of the spermatozoa as well as the reproductive tissue [26][27][28][29][30][31][32][33][34][35][36][37] . The activity level of the enzyme iso-citrate dehydrogenase recorded significant depletion in the extract fed rats when compared with that of the control indicating the deranged oxidative potential in the sperm suspension.…”
Section: Discussionmentioning
confidence: 99%