Intense Pulsed Light: review of clinical indications

Kalil, Célia Luíza Petersen Vitello; Reinehr, Clarissa Prieto Herman; Milman, Laura de Mattos

doi:10.5935/scd1984-8773.201791967

Cited by 2 publications

(3 citation statements)

References 19 publications

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“…That is, while amplitude has great relationship with absorption and penetrability, the shape of the spectrum, such as peaks and widths, has to do with the chemical constitution of the organ in question 36 . The spectral absorption range between 400 and 600 nm is related to oxyhemoglobin, hemoglobin and melanin 37 .…”

Section: Discussionmentioning

confidence: 99%

Study of laser fluorescence spectroscopy in livers of rats with hypothermic ischemia

Tsuge,

Pereira,

Vollet-Filho

et al. 2023

Acta Cir. Bras.

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Purpose: After partial hepatectomy (PH), the remaining liver (RL) undergoes regenerative response proportional to the host.Limited literature exists on hepatic viability after tissue injury during hypothermic preservation. Spectroscopy measures cellular fluorescence and is explored for tissue characterization and parameter investigation. This study aimed to assess fluorescence analysis (spectroscopy) in evaluating liver viability and its relationship with hepatic tissue regeneration 24 hours after PH. Additionally, we analyzed liver regeneration in RL after 70% partial hepatectomy under hypothermic conditions with laser irradiation. Methods:Fifty-six Wistar rats were divided into four groups: total non-perfused liver (control), total perfused liver, partial hepatectomy "in situ", and partial hepatectomy "ex situ". Tissue analysis was performed at 0 and 24 hours using spectroscopy with laser devices emitting at 532 (green) and 405 nm (violet). Results: Spectroscopy identified tissue viability based on consistent results with Ki67 staining. The fluorescence spectra and Ki67 analysis displayed similar patterns, linking proliferative activity and absorption intensity. Conclusion:Fluorescence spectroscopy proves to be promising for real-time analysis of cellular activity and viability. Metabolic activity was observed in groups of live animals and hypothermically preserved samples, indicating cellular function even under blood deprivation and hypothermic conditions.

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Section: Discussionmentioning

confidence: 99%

Study of laser fluorescence spectroscopy in livers of rats with hypothermic ischemia

Tsuge,

Pereira,

Vollet-Filho

et al. 2023

Acta Cir. Bras.

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“…21 Today, the incorporation of a new technology, known as optimal pulse technology, ensures that light is evenly distributed to the skin surface during each pulse, decreasing the risk of side effects such as postoperative purpura. 21,36 In addition, modern technology allows clinicians to simultaneously target several different chromophores at different locations in the skin. This generation of IPL has garnered more attention as a potential tool for many skin conditions and there has been more evidence to support its greater efficacy.…”

Section: Fourth Generation (2004-present): Modern Technologymentioning

confidence: 99%

“…Older technologies that contained spiked pulses caused higher incidences of thrombosis and vascular rupture due to the initial energy peak compared to modern machines 21 . Today, the incorporation of a new technology, known as optimal pulse technology, ensures that light is evenly distributed to the skin surface during each pulse, decreasing the risk of side effects such as postoperative purpura 21,36 . In addition, modern technology allows clinicians to simultaneously target several different chromophores at different locations in the skin.…”

Section: History Of Ipl Therapymentioning

confidence: 99%

Intense pulsed light for the treatment of pigmented and vascular disorders and lesions: A review

Fischer

Han

Gade

et al. 2020

Dermatological Reviews

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Background: Intense pulsed light (IPL) technology has evolved since its first introduction to the market in the 1990s. The underlying mechanism, similar to that of lasers, involves selective thermal damage to specific targets. IPL uses flashlamps and bandpass filters to emit pulsed light of adjustable wavelengths, fluences, and pulse durations. These features contribute to its versatility in treating a wide range of dermatological conditions.Aims: The purpose of this review is to highlight the history, mechanisms of action, and clinical applications of IPL in treating pigmented and vascular lesions, and to present a comparison of commonly-used IPL devices available to the market.Materials and Methods: A literature search was conducted using electronic databases (Medline, Pubmed, Embase, CINAHL, EBSCO) and textbooks, in addition to the authors' clinical experience on IPL therapy, and findings are presented here.Results: Studies have demonstrated IPL to be an efficacious and safe modality for treating a variety of pigmented and vascular disorders and lesions, including postinflammatory hyperpigmentation, melasma, ephelides and solar lentigines, telangiectasias, port-wine stains, poikiloderma of Civatte, rosacea, hemangiomas, venous malformations, and is comparable to other standard therapeutic options.Literature is supportive yet limited due to small sample sizes and short follow-up periods.Discussion: The adaptability and affordability of IPL often deem it a favorable primary or adjunctive option for treating benign pigmented and vascular skin lesions. IPL technology has evolved over time and modern devices are similar in both efficacy and side effect profile.

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Intense Pulsed Light: review of clinical indications

Cited by 2 publications

References 19 publications

Study of laser fluorescence spectroscopy in livers of rats with hypothermic ischemia

Study of laser fluorescence spectroscopy in livers of rats with hypothermic ischemia

Intense pulsed light for the treatment of pigmented and vascular disorders and lesions: A review

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