Intensified Reaction and Separation Systems

Abstract

Process intensification follows four main goals: to maximize the effectiveness of intra- and intermolecular events, to give each molecule the same processing experience, to optimize the driving forces/maximize specific interfacial areas, and to maximize the synergistic effects of partial processes. This paper shows how these goals can be reached in reaction and separation systems at all relevant time and length scales and is focused on the structuring of reactors and separation units, on the use of different energy forms to improve the reaction and separation, on combining and superimposing of different phenomena in one integrated unit or reactor, and on the application of oscillations for intensification of reaction and separation processes.

Reactive Distillation for Multiple-Reaction Systems: Optimisation Study Using an Evolutionary Algorithm

“…Compared to conventional reaction-separation sequences, such so-called integrated reactive separation processes offer the potential for large savings of capital, energy, and materials (Górak and Stankiewicz, 2011;van Gerven and Stankiewicz, 2009)). One of the most important industrial applications of the integrated reactive-separation concept is reactive distillation (RD), in which reaction and distillation occur at the same time and in the same location (Schoenmakers and Bessling, 2003).…”

Deterministic global optimization in conceptual process design of distillation and melt crystallization

“…However, owing to its relatively low thermodynamic efficiency distillation has a significant energy demand, amounting for up to 50 % of costs in chemical plants [26,27]. The combination of energy-efficient unit operations, such as melt crystallization or organic solvent nanofiltration, with distillation in hybrid processes is a promising approach for increasing the energy and resource efficiency as well as decreasing the capital and operating costs [28]. The combination of distillation and melt crystallization is relatively well known for separation of close boiling mixtures and azeotropes.…”

Kontinuierliche Durchflussverfahren: ein Werkzeug für die sichere Synthese von pharmazeutischen Wirkstoffen

“…[10,11] Die erhçhte Reaktionsgeschwindigkeit bei hohen Temperaturen steigert wiederum die Produktivität und verringert die Stellfläche der Anlage,r esultierend in einem kostengünstigeren Gesamtprozess (d. h. Prozessintensivierung). [10,12] Darüber hinaus führen Automatisierung und Inline-Monitoring zur Verbesserung der Qualität und Uniformität der Produkte. [13] Wichtig ist, dass durch den außergewçhnlichen Wärmeaustauschgrad der Mikroreaktoren die Ausbildung von Überhitzungszonen, Te mperaturgradienten oder Wärmestau und eine damit einhergehende Verringerung der Reaktionsselektivität, selbst bei schnellen und stark exothermen Reaktionen, unterbunden werden.…”