Intensity modulated radiation therapy for oropharyngeal and oral cavity tumors: clinical use and experience

Osteoradionecrosis in cancer patients: the evidence base for treatment-dependent frequency, current management strategies, and future studies

“…& Four studies included consideration of IMRT, a targeted cancer therapy, relative to ORN prevention [23][24][25][26]. These studies collectively demonstrated that although the weighted prevalence with IMRT was lower than with conventional RT (5.2% vs. 7.3%, respectively), additional studies are needed to determine if this difference is clinically significant.…”

Radiosurgery for Desmoplastic Melanoma of the Head and Neck Using the Leksell Gamma Knife Perfexion Technology

“…However, long-term IMRT outcome data are limited because of significant variation between centers in IMRT delivery technique, including target delineation and dose prescription. Claus et al [10] reported repeat IMRT in 8 patients who had recurrent head and neck cancer; severe acute radiation reactions developed in 2 patients (grade 3 mucositis), 2 patients suffered grade 3 dysphagia, and 4 patients had grade 3 pain. Biagioli et al [11] reported that after repeat IMRT in 41 patients with recurrent head and neck cancer, grade 3 or 4 acute adverse radiation toxicities developed in 31.7%.…”

IMRT for Carcinomas of the Oropharynx and Oral Cavity

“…The value of IMRT in the re-irradiation of HNSCCs has enormous potential and has been explored in several centers [11]. In addition to conformal avoidance, reirradiation will require the reporting of highly quantitative data sets that should be uniformly applied to these challenging clinical situations.…”