Global software development (GSD) practice has been increasingly emerging in the recent few decades in the field of business and software industry. On the one hand, many software development organizations get the benefits of GSD, including but not limited to reduced cost, cheap labor, round the clock working and skilled professionals. On the other hand, these organizations have to face several challenges because of GSD. These challenges pose serious threats to the stability of the GSD projects. Communication between distributed team members is one of the most crucial challenges in GSD. Therefore, the current study aims to identify the communication risk in GSD and also evaluate the impact of these communication risks in GSD environment. A Systematic Literature Review (SLR) has been performed to identify all the communication-related issues in GSD. After that, a conceptual framework has been proposed for evaluating the impact of those issues on communication risk in GSD. An empirical evaluation has been performed on data collected from the software organizations of Pakistan working in GSD based environment. The finding of our study demonstrates that geographical distance, socio-temporal distance, socio-culture distance, team member's attitude, team issues, organizational & architectural issue and customer issue have a significant direct impact on communication risk in GSD. The study also shows that there is a significant correlation between findings of SLR and empirical investigation (r = 0.460, P = 0.005). Further, we believe that the results of our research can help to tackle the issues related to communication in GSD. Therefore, it will help to improve the performance of the development activities of GSD organizations.