Interaction between cardiovascular system and respiration

Tsai, Nan-Chyuan; Lee, Rong Mao

doi:10.1016/j.apm.2011.04.033

Cited by 9 publications

(12 citation statements)

References 14 publications

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“…The results of this study underscore that respiratory and circulatory conditions ( 31 ), such as asthma ( 32 ) and cerebral infarction ( 33 ), significantly elevate the risk of CI. The observed increase in odds ratios for asthma and cerebral infarction emphasizes the need for vigilant monitoring and management in patients with these conditions.…”

Section: Discussionmentioning

confidence: 56%

Assessing cognitive impairment in home-dwelling Chinese elders aged 80+: a detailed survey of 13,000 participants focusing on demographic factors, social engagement, and disease prevalence

Bian,

Tian,

Meng

et al. 2024

Front. Psychiatry

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IntroductionCognitive Impairment (CI) in the elderly, encompassing conditions ranging from Mild Cognitive Impairment (MCI) to dementia, represents a growing public health concern globally. This study aims to investigate the prevalence and correlates of CI among individuals aged 80 and above.MethodsThe study conducts 13,027 elderly individual’s door-to-door surveys, followed by the cross-tabulation of analysis data, logistic regression analysis, and health condition assessments to examine various determinants of CI.ResultsThe current study’s key findings demonstrate sub-statical correlations between CI and various factors, including educational attainment, marital status, and gender. Pronounced differences are evident between urban and rural demographics. Furthermore, aspects of social engagement, notably communication proficiency and sensory capabilities, exhibit a strong association with CI. Logistic regression analysis highlights that residing in rural areas (Odds Ratio [OR] = 0.637) and being female (OR = 0.71) are linked to a decreased risk of CI. In contrast, behavioral and health-related variables present a complex picture. Specifically, aggressive behavior (Adjusted OR = 1.881) and symptoms of depression (Adjusted OR = 0.549) contrast with conditions such as asthma (OR= 2.857) and cerebral infarction (OR=1.348), which elevate the risk of CI. Intriguingly, hyperlipidemia (OR= 0.671) appears to confer a protective effect against CI.ConclusionThe study highlights the complexity of factors affecting CI in the elderly, advocating for a comprehensive approach to understanding and managing cognitive health.

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Section: Discussionmentioning

confidence: 56%

Assessing cognitive impairment in home-dwelling Chinese elders aged 80+: a detailed survey of 13,000 participants focusing on demographic factors, social engagement, and disease prevalence

Bian,

Tian,

Meng

et al. 2024

Front. Psychiatry

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“…19 These pathologies are all associated with oxidative stress and an increase resistance of pulmonary flow that will adversely affect gas exchange and ultimately blood oxygen levels. 1,20 Aetiological risk factors include the exposure to environmental pollutants such as heavy metals from smoking and cooking with solid fuels. 4 Usually, heavy metals are generally found as mixtures of two or more metals, and are often associated with other compounds at varying concentrations and cannot be destroyed or degraded and over time can bio-accumulate.…”

Section: Introductionmentioning

confidence: 99%

Adverse pulmonary effects after oral exposure to copper, manganese and mercury, alone and in mixtures, in a Spraque-Dawley rat model

Draper

Rooy

et al. 2023

Ultrastructural Pathology

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The rise in respiratory disease has been attributed to an increase in environmental pollution.Heavy metals contribute to environmental contamination via air, water, soil and food. The effects of atmospheric exposure to heavy metals on pulmonary structure and function have been researched, but the effects through drinking water have been neglected. The aim of this study was to investigate the potential in vivo alterations in the pulmonary tissue of male Sprague-Dawley rats after a 28-day oral exposure to copper (Cu), manganese (Mn) and mercury (Hg), alone and in mixtures, at 100 times the World Health Organisation's (WHO) safety limit for each heavy metal in drinking water. Forty-eight male Sprague-Dawley rats were randomly divided into eight groups (n=6): control, Cu, Mn, Hg, Cu + Mn, Cu + Hg, Mn + Hg and Cu, Mn + Hg. The morphology of lung tissue and the bronchioles were evaluated using light-and transmission electron microscopy. For all exposed groups, morphological changes included thickened inter-and intra-alveolar spaces, stratified epithelium, disrupted smooth muscle and early fibrosis and desquamation of the epithelia of the bronchioles to varying degrees. In all exposed groups, ultrastructurally, an increase in disarranged collagen and elastin fibres, nuclear membrane detachment, chromatin condensation, indistinct nucleoli and an increase in collagen fibre disarrangement was observed. This study has identified that oral exposure to Cu, Mn and Hg and as part of mixtures caused pathogenesis due to inflammation, cellular damage and fibrosis with Mn + Hg being the most potent heavy metal group.

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“…As to the aspect of pulmonary dynamics, computer simulation models for the human respiratory system based on mathematical models have also been developed [5]- [6]. As the heart-lung interaction is characterized by a high nonlinear behavior, it is necessary the use of combined cardiorespiratory mathematical models to describe its interrelation, and several related works have been reported to date [7]- [9].…”

Section: Introductionmentioning

confidence: 99%

Physical Model of the Cardiopulmonary System and its Interactions using the Object-Oriented Multi-Domain Environment SIMSCAPE

2023

Int’l Conference Proceedings LLTETN-23, LACBE-23, ICASCE-23 &Amp; LMEHSS-23 Dec. 11-13, 2023 Lisbon (Portugal)

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Nowadays, cardiovascular diseases together with chronic obstructive pulmonary diseases represent the main causes of natural death. On a physiological level, the cardiovascular and respiratory systems are closely related as the heart and lungs are responsible for providing nutrients to the body and removing waste substances. The use of mathematical models has contributed to a greater extent to gain an insight into the internal process that take place at cardiovascular and pulmonary level. In this paper electro-hydraulic and mechanic-electrical analogies have been employed to model the cardiovascular and respiratory systems using the SIMSCAPE physical modelling environment. Results have been obtained showing an adequate performance both under physiologic and pathophysiologic situations. The objective is to provide the clinician with a benchmark to get valuable information concerning the performance of the cardiorespiratory system and its tight interrelations.

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Interaction between cardiovascular system and respiration

Cited by 9 publications

References 14 publications

Assessing cognitive impairment in home-dwelling Chinese elders aged 80+: a detailed survey of 13,000 participants focusing on demographic factors, social engagement, and disease prevalence

Assessing cognitive impairment in home-dwelling Chinese elders aged 80+: a detailed survey of 13,000 participants focusing on demographic factors, social engagement, and disease prevalence

Adverse pulmonary effects after oral exposure to copper, manganese and mercury, alone and in mixtures, in a Spraque-Dawley rat model

Physical Model of the Cardiopulmonary System and its Interactions using the Object-Oriented Multi-Domain Environment SIMSCAPE

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