Interaction of pesticides with p-glycoprotein and other ABC proteins: A survey of the possible importance to insecticide, herbicide and fungicide resistance

Buss, David S.; Callaghan, Amanda

doi:10.1016/j.pestbp.2007.12.001

Cited by 128 publications

(104 citation statements)

References 155 publications

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“…The Ace-1 and ABCC2 genes belong to insect carboxylesterase and ATP-binding cassette (ABC) transporter gene families, whose members are involved in metabolism and regulated absorption of both insecticides and plant secondary metabolites, respectively (41)(42)(43)(44). Along with glutathione S-transferases and cytochrome P450 monooxygenases (P450s), they represent the so-called performance genes affecting growth and survival of insect larvae on host plants (45).…”

Section: Discussionmentioning

confidence: 99%

Neo-sex chromosomes and adaptive potential in tortricid pests

Nguyen

Sýkorová

Šíchová

et al. 2013

Proc. Natl. Acad. Sci. U.S.A.

115

133

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Changes in genome architecture often have a significant effect on ecological specialization and speciation. This effect may be further enhanced by involvement of sex chromosomes playing a disproportionate role in reproductive isolation. We have physically mapped the Z chromosome of the major pome fruit pest, the codling moth, Cydia pomonella (Tortricidae), and show that it arose by fusion between an ancestral Z chromosome and an autosome corresponding to chromosome 15 in the Bombyx mori reference genome. We further show that the fusion originated in a common ancestor of the main tortricid subfamilies, Olethreutinae and Tortricinae, comprising almost 700 pest species worldwide. The Z-autosome fusion brought two major genes conferring insecticide resistance and clusters of genes involved in detoxification of plant secondary metabolites under sex-linked inheritance. We suggest that this fusion significantly increased the adaptive potential of tortricid moths and thus contributed to their radiation and subsequent speciation.adaptive evolution | leaf-rollers | performance genes | sex chromosome-autosome fusion | sex-linkage

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Section: Discussionmentioning

confidence: 99%

Neo-sex chromosomes and adaptive potential in tortricid pests

Nguyen

Sýkorová

Šíchová

et al. 2013

Proc. Natl. Acad. Sci. U.S.A.

115

133

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“…Some killer toxins also have the potential to inhibit the cell cycle (Marquina et al 2002) and so differences in resistance to both benzimidazole and yeast mycocins may be due to the same target site. Alternatively, benzimidazole resistance in fungi is frequently the result of over expression of ATP binding cassette (ABC) membrane pumps (Andrade et al 2000;Buss & Callaghan 2008) which typically have low substrate specificity and so conceivably provide resistance to killer proteins and other inhibitory factors as well.…”

Section: Discussionmentioning

confidence: 99%

Candida krusei and Kloeckera apis inhibit the causal agent of pineapple fusariosis, Fusarium guttiforme

Korres¹,

Buss²,

Ventura³

et al. 2011

Fungal Biology

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“…Pretreatment with Verpamil increased the toxicity of imidacloprid, acetamiprid and thiacloprid (Figure 2.8). These effects were ascribed to the effects of the drugs on membrane bound transporter proteins (Buss and Callaghan, 2008) and suggested that the acaricides coumaphos and taufluvalinate, and 3 neonicotinoid insecticides are substrates of these transporters in insects as they are in mammals. These increases in sensitivity to the selected pesticides by inhibition of MDR (multidrug reistance) transporters were suggested to indicate that these transporters may mediate adverse synergisms of diverse toxins in bees.…”

Section: Interactions In Bees Supporting Publications 2012:en-340 120mentioning

confidence: 99%

Interaction between pesticides and other factors in effects on bees

Thompson

2012

EFS3

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Bees are important pollinators of both managed crops and wild flora. An overview of the interactions between pesticides and other factors in effects on bees considered: 1) The importance of the different exposure routes in relation to the overall exposure of bees to pesticides; 2) Multiple exposure to pesticides (including substances used in bee medication) and potential additive and cumulative effects; and 3) Interactions between diseases and susceptibility of bees to pesticides. Nectar foraging bees are likely to experienced highest exposure to both sprayed and systemic seed and soil treatments compounds followed by nurse and brood-attending bees. In both cases the major contribution to exposure was contaminated nectar with direct overspray playing a significant role in exposure. However, there are a variety of other routes (and other bee species) where there is currently insufficient data to fully total exposure: There are a large number of studies that have investigated the interactions between pesticides in bees. By far the majority have related to the interactions involving EBI fungicides and can be related to their inhibition of P450. The scale of the synergy is shown to be dose and season-dependent in acute exposures but there are few data relating to the effect of time between exposures, the effect of route of exposure or on chronic exposure effects at realistic exposure levels. There are a wide range of factors which affect the immunocompetence of bees including diet quality, pest and diseases. Although there are a limited number of laboratory based studies which suggest effects of a pesticide on disease susceptibility there is no clear evidence from field-based studies that exposure of colonies to pesticides results in increased susceptibility to disease or that there is a link between colony loss due to disease and pesticide residues in monitoring studies. KEY WORDSHoneybees, bumble bees, pesticides, disease, mixtures, synergism DISCLAIMERThe present document has been produced and adopted by the bodies identified above as author. This task has been carried out exclusively by the author(s) in the context of a contract between the European Food Safety Authority and the author, awarded following a tender procedure. The present document is published complying with the transparency principle to which the Authority is subject. It may not be considered as an output adopted by the Authority. The European food Safety Authority reserves its rights, view and position as regards the issues addressed and the conclusions reached in the present document, without prejudice to the rights of the authors. The present document has been produced and adopted by the bodies identified above as author. This task has been carried out exclusively by the author in the context of a contract between the European Food Safety Authority and the author awarded following a tender procedure. The present document is published complying with the transparency principle to which the Authority is subject. It may not be considered as...

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Interaction of pesticides with p-glycoprotein and other ABC proteins: A survey of the possible importance to insecticide, herbicide and fungicide resistance

Cited by 128 publications

References 155 publications

Neo-sex chromosomes and adaptive potential in tortricid pests

Neo-sex chromosomes and adaptive potential in tortricid pests

Candida krusei and Kloeckera apis inhibit the causal agent of pineapple fusariosis, Fusarium guttiforme

Interaction between pesticides and other factors in effects on bees

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