Interactions among gender, age, hypertension and C‐reactive protein in coronary vasospasm

Hung, Ming-Yow; Hsu, Kuang‐Hung; Hung, Ming‐Jui; Cheng, Chi Wen; Cherng, Wen Jin

doi:10.1111/j.1365-2362.2010.02360.x

Cited by 45 publications

(37 citation statements)

References 45 publications

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“…For example, the frequency of CAS appears to be greater in the Japanese population than that in western populations 12 and the diagnosis of variant angina among patients with angina referred to Japanese medical institutions is made in a high percentage, 40% 9. In addition, the frequencies of multiple spasms (≥2 spastic coronary arteries) by provocative testing in Japanese (24.3%) 13 and Taiwanese populations (19.3%) 14 are markedly higher than those in Caucasians (7.5%) 15. In East Asia as well as Western countries, CAS is more prevalent among men than women 9,14.…”

Section: Epidemiologymentioning

confidence: 96%

“…In addition, the frequencies of multiple spasms (≥2 spastic coronary arteries) by provocative testing in Japanese (24.3%) 13 and Taiwanese populations (19.3%) 14 are markedly higher than those in Caucasians (7.5%) 15. In East Asia as well as Western countries, CAS is more prevalent among men than women 9,14. Most patients with CAS are between 40 and 70 years of age, and the prevalence tends to decrease after the age of 70 years 9,14.…”

Section: Epidemiologymentioning

confidence: 99%

“…In East Asia as well as Western countries, CAS is more prevalent among men than women 9,14. Most patients with CAS are between 40 and 70 years of age, and the prevalence tends to decrease after the age of 70 years 9,14. Previous Asian studies of patients without obstructive coronary artery disease have shown that the prevalence of CAS is around 50% in patients with angina and 57% in patients with acute coronary syndrome 16,17.…”

Section: Epidemiologymentioning

confidence: 99%

“…It has been shown that while the older subjects are more likely to develop CAS than their younger analogs, smoking has a stronger effect on CAS occurrence in the younger than in their older counterparts 47. Furthermore, those factors may be gender-specific, as smoking and age seem to play a more significant role in men 14,45. While active smokers constitute 45-75% of patients with CAS, 25-55% of patients do not smoke 45,48,49.…”

Section: Risk Factors and Precipitating Factorsmentioning

confidence: 99%

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Coronary Artery Spasm: Review and Update

Hung¹,

Hu²,

Hung³

2014

Int. J. Med. Sci.

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167

145

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Coronary artery spasm (CAS), an intense vasoconstriction of coronary arteries that causes total or subtotal vessel occlusion, plays an important role in myocardial ischemic syndromes including stable and unstable angina, acute myocardial infarction, and sudden cardiac death. Coronary angiography and provocative testing usually is required to establish a definitive diagnosis. While the mechanisms underlying the development of CAS are still poorly understood, CAS appears to be a multifactorial disease but is not associated with the traditional risk factors for coronary artery disease. The diagnosis of CAS has important therapeutic implications, as calcium antagonists, not β-blockers, are the cornerstone of medical treatment. The prognosis is generally considered benign; however, recurrent episodes of angina are frequently observed. We provide a review of the literature and summarize the current state of knowledge regarding the pathogenesis of CAS.

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Section: Epidemiologymentioning

confidence: 96%

Section: Epidemiologymentioning

confidence: 99%

Section: Epidemiologymentioning

confidence: 99%

Section: Risk Factors and Precipitating Factorsmentioning

confidence: 99%

See 2 more Smart Citations

Coronary Artery Spasm: Review and Update

Hung¹,

Hu²,

Hung³

2014

Int. J. Med. Sci.

Self Cite

167

145

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“…Кроме того, частота многососудистого спазма (спазм не менее 2 коронарных артерий) путем прово-кационного тестирования японского (24,3%) [3] и тай-ваньского населения (19,3%) [4] заметно выше, чем у европеоидов (7,5%) [5].…”

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Modern diagnostic capabilities for vasospastic angina diagnostics (intracoronary provocative testing)

Обединский¹,

Бугуров²,

Крестьянинов³

et al. 2017

PKiK

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This review is devoted to a topical problem of modern cardiology – techniques of diagnosing vasospastic angina. The results of retrospective and prospective studies on the efficacy and safety of vasospastic angina diagnostics are reviewed. The literature on the prevalence, progression and treatment of this pathology is discussed.Received 13 January 2017. Accepted 6 February 2017.Financing: The study did not have sponsorship.Conflict of interest: The authors declare no conflict of interest.

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Role of Pre-procedural C-reactive Protein Level in the Prediction of Major Adverse Cardiac Events in Patients Undergoing Percutaneous Coronary Intervention: a Meta-analysisof Longitudinal Studies

et al. 2014

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Numerous studies have reported the relation between pre-procedural C-reactive protein (CRP) levels and the risk of major adverse cardiac events (MACEs) in patients undergoing percutaneous coronary intervention (PCI). However, the results across the studies were inconsistent. The aim of this study was to evaluate the predictive effect of pre-procedural CRP levels and the risk of MACEs in patients undergoing PCI. Longitudinal studies on the association between pre-procedural CRP levels and MACEs were identified by electronic and manual searches. Summary risk ratios (RRs) and 95 % confidence intervals (CI) were calculated employing an inverse variance random-effects model irrespective of between-study heterogeneity. Thirty-three studies involving 34,367 patients with 4119 MACEs were included in this study. High CRP level was associated with increased incidences of MACEs, all-cause death, myocardial infarction, coronary revascularization, and clinical restenosis, with pooled RRs of 1.97 (95 % CI, 1.65, 2.35), 2.88 (95 % CI, 2.15, 3.86), 1.81 (95 % CI, 1.48, 2.21), 1.31 (95 % CI, 1.11, 1.56), and 1.45 (95 % CI, 1.07, 1.96), respectively. Dose-response analysis showed that every 1 mg/L increment in pre-procedural serum CRP level was associated with a significant 12 % increase in the risk of MACEs. In spite of heterogeneity across the included studies, this meta-analysis suggests that pre-procedural serum CRP level is a valuable predictor of MACEs in patients undergoing PCI.

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Interactions among gender, age, hypertension and C‐reactive protein in coronary vasospasm

Cited by 45 publications

References 45 publications

Coronary Artery Spasm: Review and Update

Coronary Artery Spasm: Review and Update

Modern diagnostic capabilities for vasospastic angina diagnostics (intracoronary provocative testing)

Role of Pre-procedural C-reactive Protein Level in the Prediction of Major Adverse Cardiac Events in Patients Undergoing Percutaneous Coronary Intervention: a Meta-analysisof Longitudinal Studies

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