Interactions of N-heteroalkylaminomethylenebisphosphonic acids with Cd(II) ions: Electrochemical and spectroscopic investigations

Dobosz, Agnieszka; Spychała, Jan; Ptak, Tomasz; Maciejewska, Gabriela; Chmielewska, Ewa; Kafarski, Paweł; Młynarz, Piotr

doi:10.1016/j.ica.2015.05.034

Cited by 12 publications

(3 citation statements)

References 32 publications

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“…3a). It is an advantage that Ale contains bisphosphonate moieties with a strong binding a nity to a number of metal ions, such as alkaline earth [43,44] and transition metals [45], as well as lanthanides [46]. The presence of phosphonate groups in the Ale-P(DMA-AEC-Boc)-DY-615 and Ale-P(DMA-AMPS)-DY-615 was con rmed by 31 P NMR spectroscopy (Figure S3).…”

Section: Resultsmentioning

confidence: 94%

Poly(N,N-dimethylacrylamide)-Coated Upconverting NaYF4:Yb,Er@NaYF4:Nd Core-Shell Nanoparticles For Fluorescent Labeling of Carcinoma Cells

Oleksa

Macková

Engstová

et al. 2021

Preprint

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Upconverting luminescent lanthanide-doped nanoparticles (UCNP) belong to promising new materials that absorb infrared light able to penetrate in the deep tissue level, while emitting photons in the visible or ultraviolet region, which makes them favorable for bioimaging and cell labeling. Here, we have prepared upconverting NaYF4:Yb,Er@NaYF4:Nd core-shell nanoparticles, which were coated with copolymers of N,N-dimethylacrylamide (DMA) and 2-(acryloylamino)-2-methylpropane-1-sulfonic acid (AMPS) or tert-butyl [2-(acryloylamino)ethyl]carbamate (AEC-Boc) with negative or positive charges, respectively. The copolymers were synthesized by a reversible addition-fragmentation chain transfer (RAFT) polymerization, reaching Mn ~11 kDa and containing ~5 mol.% of reactive groups. All copolymers contained bisphosphonate end-groups to be firmly anchored on the surface of NaYF4:Yb,Er@NaYF4:Nd core-shell nanoparticles. To compare properties of polymer coatings, poly(ethylene glycol)-coated and neat UCNP were used as a control. UCNP with various charges were then studied as labels of carcinoma cells, including human hepatocellular carcinoma HepG2, human cervical cancer HeLa, and rat insulinoma INS-1E cells. All the particles proved to be biocompatible (nontoxic); depending on their ξ-potential, the ability to penetrate the cells differed. This ability together with the upconversion luminescence are basic prerequisites for application of particles in photodynamic therapy (PDT) of various tumors, where emission of nanoparticles in visible light range at ~650 nm excites photosensitizer.

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Section: Resultsmentioning

confidence: 94%

Poly(N,N-dimethylacrylamide)-Coated Upconverting NaYF4:Yb,Er@NaYF4:Nd Core-Shell Nanoparticles For Fluorescent Labeling of Carcinoma Cells

Oleksa

Macková

Engstová

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…3 a). It is an advantage that Ale contains bisphosphonate moieties with a strong binding affinity to a number of metal ions, such as alkaline earth 45 , 46 and transition metals 47 , as well as lanthanides 48 . The presence of phosphonate groups in the Ale-P(DMA-AEC-Boc)-DY-615 and Ale-P(DMA-AMPS)-DY-615 was confirmed by 31 P NMR spectroscopy (Fig.…”

Section: Resultsmentioning

confidence: 99%

Poly(N,N-dimethylacrylamide)-coated upconverting NaYF4:Yb,Er@NaYF4:Nd core–shell nanoparticles for fluorescent labeling of carcinoma cells

Oleksa

Macková

Engstová

et al. 2021

Sci Rep

View full text Add to dashboard Cite

Upconverting luminescent lanthanide-doped nanoparticles (UCNP) belong to promising new materials that absorb infrared light able to penetrate in the deep tissue level, while emitting photons in the visible or ultraviolet region, which makes them favorable for bioimaging and cell labeling. Here, we have prepared upconverting NaYF4:Yb,Er@NaYF4:Nd core–shell nanoparticles, which were coated with copolymers of N,N-dimethylacrylamide (DMA) and 2-(acryloylamino)-2-methylpropane-1-sulfonic acid (AMPS) or tert-butyl [2-(acryloylamino)ethyl]carbamate (AEC-Boc) with negative or positive charges, respectively. The copolymers were synthesized by a reversible addition-fragmentation chain transfer (RAFT) polymerization, reaching Mn ~ 11 kDa and containing ~ 5 mol% of reactive groups. All copolymers contained bisphosphonate end-groups to be firmly anchored on the surface of NaYF4:Yb,Er@NaYF4:Nd core–shell nanoparticles. To compare properties of polymer coatings, poly(ethylene glycol)-coated and neat UCNP were used as a control. UCNP with various charges were then studied as labels of carcinoma cells, including human hepatocellular carcinoma HepG2, human cervical cancer HeLa, and rat insulinoma INS-1E cells. All the particles proved to be biocompatible (nontoxic); depending on their ξ-potential, the ability to penetrate the cells differed. This ability together with the upconversion luminescence are basic prerequisites for application of particles in photodynamic therapy (PDT) of various tumors, where emission of nanoparticles in visible light range at ~ 650 nm excites photosensitizer.

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“…The study of the metal organic coordination polymers containing with d 10 electron configuration metal ions becomes a trend because of their potential applications in the field of photoactive materials for light emitting diodes (LEDs), chemical sensors and electrochemical displays [52][53][54].…”

Section: Synthesis Spectroscopic Characterization and Thermal Analysismentioning

confidence: 99%

Structural diversification and photocatalytic properties of three Cd(II) coordination polymers decorated with different auxiliary ligands

Yin

Zhuang

Huang

et al. 2016

Journal of Solid State Chemistry

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Three cadmium coordination polymers, [Cd(bismip)] n (1), {[Cd(bismip)(phen)]•H 2 O} n (2) and {[Cd 2 (bismip) 2 (4,4'-bipy)]•2H 2 O} n (3) (H 2 bismip = 5-(1H-benzoimidazol-2-ylsulfanylmethyl)-isophthalic acid, phen = 1,10-phenanthroline, 4,4'-bipy = 4,4'-bipyridine) have been prepared under solvothermal conditions. In 1, the [Cd 4 (bismip) 3 ] units are jointed by bismip ligands to afford a three-dimensional (3D) architecture. Complex 2 exhibits a 3D supramolecular framework based on the interconnection of 1D chains through hydrogen bonding interactions and π-π packing interactions. 3 is a twofold interpenetrating 3D architecture with a (4•8 2)(4 2 •8 4) Schläfli symbol in which 2D layers are interlinked by 4,4'-bipy ligands. The diverse structures of compounds 1-3 indicate that the auxiliary ligands have significant effects on the final structures. The photoluminescent properties and photocatalytic properties of these coordination polymers in the solid state were also investigated. Remarkably, 3 shows the wide gap semiconductor nature and exhibit excellent photocatalytic performance.

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Interactions of N-heteroalkylaminomethylenebisphosphonic acids with Cd(II) ions: Electrochemical and spectroscopic investigations

Cited by 12 publications

References 32 publications

Poly(N,N-dimethylacrylamide)-Coated Upconverting NaYF4:Yb,Er@NaYF4:Nd Core-Shell Nanoparticles For Fluorescent Labeling of Carcinoma Cells

Poly(N,N-dimethylacrylamide)-Coated Upconverting NaYF4:Yb,Er@NaYF4:Nd Core-Shell Nanoparticles For Fluorescent Labeling of Carcinoma Cells

Poly(N,N-dimethylacrylamide)-coated upconverting NaYF4:Yb,Er@NaYF4:Nd core–shell nanoparticles for fluorescent labeling of carcinoma cells

Structural diversification and photocatalytic properties of three Cd(II) coordination polymers decorated with different auxiliary ligands

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