“…Compared to previous work, 62 this paper presents advancements in the manufacturing technology of soft robots, enabling the reversible and programmable functionality of a single-layer hydrogel robot. Besides, if combined with flexible sensing, 63 multi-physical cooperative driving, 64,65 and therapeutic capabilities, 66,67 the single-layer hydrogel robot could realize the integration of diagnosis and treatment and environmental monitoring in the biomedical field. For instance, the integration of temperature-responsive color changes could potentially enable the realization of an unconstrained environmental monitoring system and locally driven soft robot systems.…”