Interdevice comparison of retinal sensitivity assessments in a healthy population: the CenterVue MAIA and the Nidek MP-3 microperimeters

Balasubramanian, Siva; Uji, Akihito; Lei, Jianqin; Velaga, Swetha Bindu; Nittala, Muneeswar Gupta; Sadda, Srinivas R

doi:10.1136/bjophthalmol-2017-310258

Cited by 37 publications

(33 citation statements)

References 12 publications

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“…This outcome is consistent with that of À0.01 to À0.02 dB/year for microperimetry [40][41][42] and of À0.04 to À0.08 dB/year for SAP within 108. 15,17 In addition, the ranges of sensitivity values are consistent with those reported for ocular healthy individuals 43,44 and for those with AMD. 45,46 A limitation of the study is that the conclusion refers to those with AMD and warrants evaluation in visual field loss arising from other disease entities.…”

Section: Discussionsupporting

confidence: 85%

Microperimetry in Age-Related Macular Degeneration: An Evidence-Base for Pattern Deviation Probability Analysis in Microperimetry

Cassels

Wild

Margrain

et al. 2019

Trans. Vis. Sci. Tech.

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Purpose: The ''traffic light'' color designation of differential light sensitivity used in a number of microperimeters does not encompass the conventional Total and Pattern Deviation probability analyses adopted by standard automated perimetry. We determined whether the color designation is indicative of abnormality as represented by the ''gold standard'' Pattern Deviation probability analysis. Methods: Total and Pattern Deviation probability levels, using two different methods, were derived at each of 40 stimulus locations, within 78 eccentricity, from 66 ocular healthy individuals (66 eyes) who had undergone microperimetry with the Macular Integrity Assessment microperimeter. The probability levels were applied to the corresponding fields from each of 45 individuals (45 eyes) with age-related macular degeneration (AMD) and evaluated in relation to the color designation. Results: Sensitivities designated in orange encompassed the entire range of Pattern Deviation probability levels (from normal to P 1%). Those designated in green were mostly normal; those in red/black generally corresponded to the 1% probability level. Conclusions: The green and the red/black designations are generally indicative of normal and abnormal probability values, respectively. The orange designation encompassed all probability outcomes and should not be relied upon for visual field interpretation. The evidence base indicates replacement of the color designation of sensitivity in AMD by Total Deviation and Pattern Deviation analyses. Translational Relevance: The use of Total and Pattern Deviation probability analyses is not universal in all microperimeters, and the derivation of these values indicates that color coding will lead to errors in evaluating visual field loss.

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Section: Discussionsupporting

confidence: 85%

Microperimetry in Age-Related Macular Degeneration: An Evidence-Base for Pattern Deviation Probability Analysis in Microperimetry

Cassels

Wild

Margrain

et al. 2019

Trans. Vis. Sci. Tech.

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“…This finding confirms previous studies that the dynamic range of the system is limited particularly with regard to detection of slight mesopic retinal sensitivity loss. 11,25 Further improvements, such as the introduction of the MP-3 and other FCP devices, may overcome this limitation in the future.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7] Various studies have reported functional impairment in AMD patients beyond the reduction of best-corrected central visual acuity, including reading speed, low-luminance visual acuity, dark adaptometry, and fundus-controlled perimetry (FCP). [8][9][10][11][12] For the latter, early studies showed localized reduction of mesopic sensitivity over drusen and pigmentary changes. 13,14 Further developments of the MP-1S device (Nidek Technologies, Padova, Italy) led to the possibility of scotopic testing under dark-adapted conditions.…”

mentioning

confidence: 99%

Structure-Function Analysis in Patients With Intermediate Age-Related Macular Degeneration

Saßmannshausen

Steinberg

Fimmers

et al. 2018

Invest. Ophthalmol. Vis. Sci.

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“…The maximum luminance of the MP-3 is 10,000 asb, and the stimulus dynamic range is between 0 and 34 dB. [10][11][12][13][14] Only reliable test results (a false-positive rate of <20% and a false-negative rate of <25%) were used in the analyses, as in the HFV SITA test results set in the present study. A fixation loss is not applicable because the MP-3 has an autotracking system, making it possible to project the stimulus only at predefined retinal positions.…”

Section: Functional Dfr Angle Measurementmentioning

confidence: 99%

“…The novel MP-3 microperimeter (NIDEK Co., Ltd., Aichi, Japan) measures visual field sensitivity by projecting a target light directly onto the region of interest on the retina rather than onto a screen. 10,11 The retina position is automatically tracked and the stimulus location is aligned accordingly, resulting in precise determination of retinal test locations stimulated at each target presentation. Compared with the HVF test, this full-autotracking system makes it possible to measure sensitivities more accurately, at exact test points.…”

mentioning

confidence: 99%

Discordance of Disc-Fovea Raphe Angles Determined by Optical Coherence Tomography and MP-3 Microperimetry in Eyes With a Glaucomatous Hemifield Defect

Mori

Kurimoto

Kanamori

et al. 2019

Invest. Ophthalmol. Vis. Sci.

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The purpose of this study was to evaluate the concordance of a temporal raphe architecture estimated using optical coherence tomography (OCT) and MP-3 microperimetry. METHODS. We enrolled 25 eyes with either an upper or lower glaucomatous hemifield defect, as detected on the Humphrey visual field 30-2 test. A structural temporal raphe was extrapolated from visible end points of retinal nerve fiber bundles present in a perimetrically normal hemiretina on an en face Spectralis OCT image. A functional temporal raphe was drawn as a line from the fovea to the border of at least a 10-dB difference in sensitivity, at vertically adjacent test points, with at least three consecutive pairs among 25 test points placed at 88 to 188 from the fovea (28 intervals) on the MP-3. An angle determined by the optic disc center, the fovea, and the temporal raphe line (the DFR angle) was calculated. Correlations and agreement of the OCT-and MP-3-derived DFR angles and factors affecting discordance of the two estimates were evaluated. RESULTS. Despite no significant demographic differences, the functional DFR angle (mean 6 SD, 171.88 6 3.58) was significantly larger than that of the structural DFR angle (166.58 6 3.28) in 14 eyes with upper hemifield defects and vice versa in 11 eyes with lower hemifield defects (163.48 6 3.08 vs. 170.58 6 3.28). The mean deviation was significantly associated with the functional and structural DFR angle difference in eyes with only upper hemifield defects. CONCLUSIONS. The structural temporal raphe was more deviated to the perimetrically normal hemiretina side than to the functional temporal raphe, thereby suggesting that a structural change may precede a functional loss.

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Interdevice comparison of retinal sensitivity assessments in a healthy population: the CenterVue MAIA and the Nidek MP-3 microperimeters

Cited by 37 publications

References 12 publications

Microperimetry in Age-Related Macular Degeneration: An Evidence-Base for Pattern Deviation Probability Analysis in Microperimetry

Microperimetry in Age-Related Macular Degeneration: An Evidence-Base for Pattern Deviation Probability Analysis in Microperimetry

Structure-Function Analysis in Patients With Intermediate Age-Related Macular Degeneration

Discordance of Disc-Fovea Raphe Angles Determined by Optical Coherence Tomography and MP-3 Microperimetry in Eyes With a Glaucomatous Hemifield Defect

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