Intérêt du mélange équimolaire d’oxygène et de protoxyde d’azote (Meopa) dans les biopsies transrectales de prostate

Spie, R.; Watfa, J.; Dubruille, Thomas; Michel, Frédéric

doi:10.1016/j.purol.2008.03.028

Cited by 11 publications

(11 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…McIntyre et al [ 27 ] also achieved a significant reduction in pain scores of the nitrous oxide group (median 1.1) compared with the control (air) group (median 3.4) (p < 0.001). A different result was observed by Spie et al[ 28 ], who did not find a significant difference, although pain tended to be lower in the nitrous oxide group (mean 2.9 in the nitrous oxide group and 3.5 in the control group, p = 0.10).…”

Section: Discussioncontrasting

confidence: 70%

See 1 more Smart Citation

A 50-50% mixture of nitrous oxide-oxygen in transrectal ultrasound-guided prostate biopsy: A randomized and prospective clinical trial

et al. 2018

View full text Add to dashboard Cite

IntroductionTransrectal ultrasound-guided biopsy (TUSPB) is the standard method of diagnosis for prostate cancer, and although it is well tolerated by some patients, it presents a discomfort rate of 65 to 90%, which may be associated with pain. For convenience, it is agreed that a method of analgesia and sedation is necessary. For this purpose, this study aimed to evaluate the impact of inhalation of a 50–50% N2O-O2 gas mixture on pain intensity in these patients.Material and methodsRandomized, double-blinded clinical trial, conducted at Antônio Pedro University Hospital (Hospital Universitário Antônio Pedro), Niterói, RJ, Brazil, containing two groups of 42 patients: a control (C) group, which received 100% oxygen inhalation, and a nitrous oxide (NO) group, which received inhalation of the 50–50% N2O-O2 mixture, self-administered during TUSPB. The pain intensity and degree of satisfaction were evaluated through a visual analogue scale (VAS), as was the frequency of adverse events.ResultsEighty-four patients were included in the study, with 42 in each group. The mean pain intensity was lower in the NO group than in the C group [2.52 (0–10) vs 5.95 (0–10), p < 0.001], and the degree of satisfaction was higher in the NO group than in the C group (8.14 vs. 4.69, p < 0.001). The adverse effects were somnolence, dizziness, nausea, vomiting, discomfort and euphoria without differences between the groups.ConclusionThe 50–50% N2O-O2 mixture was effective in reducing pain intensity and increasing the degree of satisfaction in TUSPB, with tolerable side effects.

show abstract

Section: Discussioncontrasting

confidence: 70%

“…Spie et al [ 28 ] found lower pain intensity values in the control group (mean of 3.5) than those observed in the present study (mean 5.95) and the study by Masood et al[ 16 ] (mean 5.73).…”

Section: Discussioncontrasting

confidence: 65%

A 50-50% mixture of nitrous oxide-oxygen in transrectal ultrasound-guided prostate biopsy: A randomized and prospective clinical trial

et al. 2018

View full text Add to dashboard Cite

show abstract

“…L'utilisation du MEOPA est une méthode antalgique dont l'efficacité a été montrée, chez l'adulte, dans de nombreux domaines [2, 3,5,7,14,15,20,21]. Les effets indésirables du produit sont, la plupart du temps, bénins, mineurs et cessent dès l'arrêt d'administration du MEOPA [4,16,18].…”

Section: Discussionunclassified

“…Des cas de polyneuropathies et de mégaloblastoses médul-laires avec anémie et leucopénie ont été rapportés après exposition très prolongée (toxicomanie, exposition professionnelle) [18,20]. La toxicité neurologique et hématologique est en rapport avec l'interaction du protoxyde d'azote avec le métabo-lisme de la vitamine B12 [18,20].…”

Section: Discussionunclassified

“…La toxicité neurologique et hématologique est en rapport avec l'interaction du protoxyde d'azote avec le métabo-lisme de la vitamine B12 [18,20]. Le personnel soignant est exposé directement au protoxyde d'azote dans la chambre d'un patient, dans un bloc opératoire ou dans un service médi-cal tel que la neurochirurgie, les urgences pédiatriques, l'héma-tologie pédiatrique ou encore la réanimation [16,18].…”

Section: Discussionunclassified

See 1 more Smart Citation

Prise en charge de la douleur au cours des procédures invasives en cancérologie : efficacité et acceptabilité du mélange inhalé 50 % N2O/O2 (MEOPA)

et al. 2010

View full text Add to dashboard Cite

Evolution of anxiety management in prostate biopsy under local anesthesia: a narrative review

Vanoli,

Grobet-Jeandin,

Windisch

et al. 2024

World J Urol

View full text Add to dashboard Cite

Introduction and methods Prostate biopsy (PB) is an essential step in the diagnosis and active surveillance of prostate cancer (PCa). Transperineal PB (TP-PB) is now the recommended approach and is mostly conducted under local anesthesia. However, this procedure can potentially cause anxiety for patients, given the oncological context and the fear of peri-procedural pain and complications. The objective of this narrative review is to summarize the currently available tools for the management of peri-interventional anxiety during TP-PB, with a particular emphasis on the potential role of virtual reality (VR) in this setting. Results In TP-PB, preoperative anxiety can lead to increased pain perception, longer procedure time, and decreased patient satisfaction. Pharmacological and non-pharmacological approaches have been explored to reduce anxiety, such as premedication, deep sedation, education, relaxation techniques, hypnosis, and music therapy, albeit with mixed results. VR has recently emerged in the technological armamentarium for managing pain and anxiety, and the efficiency of this technology has been evaluated in various medical fields, including pediatrics, gastroenterology, urology, gynecology, and psychiatry. Conclusion Despite the paucity of available data, VR appears to be a safe and effective technique in reducing anxiety in many procedures, even in frail patients. No studies have evaluated the role of VR in TP-PB. Future research should thus explore the optimal way to implement VR technology and any potential benefits for TP-PB patients.

show abstract

Intérêt du mélange équimolaire d’oxygène et de protoxyde d’azote (Meopa) dans les biopsies transrectales de prostate

Cited by 11 publications

References 16 publications

A 50-50% mixture of nitrous oxide-oxygen in transrectal ultrasound-guided prostate biopsy: A randomized and prospective clinical trial

A 50-50% mixture of nitrous oxide-oxygen in transrectal ultrasound-guided prostate biopsy: A randomized and prospective clinical trial

Prise en charge de la douleur au cours des procédures invasives en cancérologie : efficacité et acceptabilité du mélange inhalé 50 % N2O/O2 (MEOPA)

Evolution of anxiety management in prostate biopsy under local anesthesia: a narrative review

Contact Info

Product

Resources

About