Intermittent positive pressure respiration as a treatment in severe respiratory distress syndrome.

Delivoria‐Papadopoulos, Maria; Levison, Henry; Swyer, Paul R.

doi:10.1136/adc.40.213.474

Cited by 68 publications

(19 citation statements)

References 13 publications

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“…Our presumption that the infants selected for mechanical ventilation would have an extremely high mortality rate is supported by the observations ofothers [4,9,24]. We believe that the four infants who survived did so because mechanical ventilation was employed and overall cardiopulmonary function was thus improved.…”

Section: Resultssupporting

confidence: 64%

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Mechanical Ventilation of Newborn Infants I. The Effect of Rate and Pressure on Arterial Oxygenation of Infants with Respiratory Distress Syndrome

et al. 1969

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ExtractThis study reports the effect of varying specific parameters of mechanical ventilation on aortic PO, in six infants with severe respiratory distress syndrome. Twenty-seven studies were performed during the first 168 hours of mechanical ventilation. I n each study, arterial oxygen partial pressure was found to vary directly with airway pressure a n d inversely with respiratory rate. No correlation was found between rate and pressure, or PaO,, PaCO,, a n d p H a . Oxygenation of infants with severe respiratory distress syndrome can be significantly influenced by variation of specific parameters of mechanical ventilation independently of change in aortic carbon dioxide tension.

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Section: Resultssupporting

confidence: 64%

“…A number of authors have reported the effects of mechanical ventilation when used in infants with respiratory distress syndrome (RDS) [2,3,8,9,10,11,19,22,25,26,281. The opinion of most has been that mechanical ventilation corrects respiratory acidosis and may improve survival.…”

Section: Introductionmentioning

confidence: 99%

Mechanical Ventilation of Newborn Infants I. The Effect of Rate and Pressure on Arterial Oxygenation of Infants with Respiratory Distress Syndrome

et al. 1969

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“…3 Although physicians had long provided care to infants who were born well before their due date, the introduction of intubation and mechanical ventilation led to the creation not only of neonatal intensive care units during the ensuing decade, but also to a host of pressing ethical dilemmas. Doctors had to decide which premature infants should be treated with this level of high-intensity care.…”

Section: Historicalmentioning

confidence: 99%

Pediatric Palliative Care and Pediatric Medical Ethics: Opportunities and Challenges

Feudtner

Nathanson

2014

Pediatrics

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The fields of pediatric palliative care (PPC) and pediatric medical ethics (PME) overlap substantially, owing to a variety of historical, cultural, and social factors. This entwined relationship provides opportunities for leveraging the strong communication skills of both sets of providers, as well as the potential for resource sharing and research collaboration. At the same time, the personal and professional relationships between PPC and PME present challenges, including potential conflict with colleagues, perceived or actual bias toward a palliative care perspective in resolving ethical problems, potential delay or underuse of PME services, and a potential undervaluing of the medical expertise required for PPC consultation. We recommend that these challenges be managed by: (1) clearly defining and communicating clinical roles of PPC and PME staff, (2) developing questions that may prompt PPC and PME teams to request consultation from the other service, (3) developing explicit recusal criteria for PPC providers who also provide PME consultation, (4) ensuring that PPC and PME services remain organizationally distinct, and (5) developing well-defined and broad scopes of practice. Overall, the rich relationship between PPC and PME offers substantial opportunities to better serve patients and families facing difficult decisions.

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“…1 Early attempts used adult ventilators that were modified for neonatal use. The first widespread neonatal devices consisted of continuous flow, timecycled, pressure-limited devices to provide intermittent mandatory ventilation (IMV).…”

Section: Introductionmentioning

confidence: 99%

Neonatal ventilators: how do they differ?

Donn

2009

J Perinatol

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Remarkable technological advances over the past two decades have brought dramatic changes to the neonatal intensive care unit. Microprocessor-based mechanical ventilation has replaced time-cycled, pressure-limited, intermittent mandatory ventilation with almost limitless options for the management of respiratory failure in the prematurely born infant. Unfortunately, much of the infusion of technology occurred before the establishment of a convincing evidence base. This review focuses on the basic principles of mechanical ventilation, nomenclature and the characteristics of both conventional and high-frequency devices.

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Intermittent positive pressure respiration as a treatment in severe respiratory distress syndrome.

Cited by 68 publications

References 13 publications

Mechanical Ventilation of Newborn Infants I. The Effect of Rate and Pressure on Arterial Oxygenation of Infants with Respiratory Distress Syndrome

Mechanical Ventilation of Newborn Infants I. The Effect of Rate and Pressure on Arterial Oxygenation of Infants with Respiratory Distress Syndrome

Pediatric Palliative Care and Pediatric Medical Ethics: Opportunities and Challenges

Neonatal ventilators: how do they differ?

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