International variation in the management of infants hospitalized with respiratory syncytial virus

Behrendt, Carolyn E.; Decker, Michael D.; Burch, Daniel J.; Watson, P. H.

doi:10.1007/s004310050798

Cited by 179 publications

(142 citation statements)

References 9 publications

Supporting

Mentioning

116

Contrasting

Unclassified

Order By: Relevance

“…Despite this recommendation, previous reports indicate that up to 60% of infants with severe bronchiolitis receive corticosteroid therapy. 24,25 Our finding that Hispanic children with severe bronchiolitis were most likely to be discharged on inhaled corticosteroids is potentially concerning, as it exposes a subset of children to treatment that is not recommended. On the other hand, given the increased risk of future asthma in Hispanic communities, a higher use of inhaled corticosteroids might be seen as appropriate.…”

Section: Discussionmentioning

confidence: 99%

Racial/Ethnic differences in the presentation and management of severe bronchiolitis

et al. 2014

View full text Add to dashboard Cite

BACKGROUND AND OBJECTIVE:Bronchiolitis is the leading cause of hospitalization for US infants and is associated with increased risk of childhood asthma. Although studies have shown differences in the presentation and management of asthma across race/ethnicity, it is unclear if such differences are present for bronchiolitis. We examined if racial/ethnic differences exist in the presentation and management of severe bronchiolitis.

show abstract

Section: Discussionmentioning

confidence: 99%

Racial/Ethnic differences in the presentation and management of severe bronchiolitis

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Na Europa, lactentes admitidos no hospital por bronquite viral aguda apresentaram média de permanência de oito a nove dias 32 . Contudo, em nosso meio, as condições socioeconômicas desfavoráveis muitas vezes determinam internações prolongadas, não necessariamente relacionadas à gravidade do caso 31 .…”

Section: Resultsunclassified

Prevalência de sibilância e fatores associados em crianças indígenas Guarani hospitalizadas por doença respiratória aguda no Sul e Sudeste do Brasil

2014

View full text Add to dashboard Cite

Realizou-se estudo de prevalência de sibilância em crianças indígenas Guarani hospitalizadas por infecção respiratória aguda baixa no Sul e Sudeste do Brasil, recrutadas a partir de um sistema de vigilância implantado nas aldeias entre maio de 2007 e junho de 2008. Os dados foram extraídos por revisão dos prontuários hospitalares. Estimaram-se razões de prevalência de sibilância brutas e ajustadas segundo categorias das variáveis exploratórias, por regressão de Poisson com ajuste para variância robusta. A prevalência de sibilância foi de 58,1% (136/234). Permaneceram significativamente associadas à sibilância no modelo final: faixa etária, inversamente associada (0-11 meses: referência; 24-35 meses: 0,63, IC95%: 0,40-0,99); internação no outono (verão: referência; outono: 1,58, IC95%: 1,05-2,40); e sinais clínicos de dispneia (1,41, IC95%: 1,09-1,83), tiragem (1,42, IC95%: 1,16-1,73) e estertor (1,43, IC95%: 1,09-1,87). Os resultados revelam elevada carga de morbidade por sibilância e sugerem o fenótipo de sibilância persistente de início precoce, relacionada à recorrência de infecções respiratórias virais.

show abstract

“…Upon admission, a chest X-ray is performed on 72% of children hospitalized with RSV infection [11]. 37% of those patients have a normal chest X-ray [116].…”

Section: Predicting An Unhelpful Chest X-raymentioning

confidence: 99%

“…Examples of such supportive treatments include bronchodilator use, supplemental oxygen, intravenous hydration, parenteral antibiotic, systemic corticosteroid, intensive care, mechanical ventilation, and respiratory physiotherapy [11]. Despite many years of research, physicians are still unclear about how to optimally manage bronchiolitis patients in various care settings (ED, hospital, and outpatient), including which treatment model is the optimal one for a specific bronchiolitis patient [2,4,10,241].…”

Section: Personalized Recommendation Of Treatment Modelsmentioning

confidence: 99%

“…At present, many bronchiolitis management decisions are made subjectively [2,10]. This leads to significant practice variation, as is reflected in variable admission rates and use of specific therapies among different hospitals and physicians [1,4,[10][11][12][13][14][15][16][17][18][19][20]. Observed practice variation is not explained by differences in patient severity and has little impact on outcomes, but has a significant impact on healthcare resource usage [17].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A systematic review of predictive modeling for bronchiolitis

Luo

Nkoy

Gesteland

et al. 2014

International Journal of Medical Informatics

View full text Add to dashboard Cite

Purpose: Bronchiolitis is the most common cause of illness leading to hospitalization in young children. At present, many bronchiolitis management decisions are made subjectively, leading to significant practice variation among hospitals and physicians caring for children with bronchiolitis. To standardize care for bronchiolitis, researchers have proposed various models to predict the disease course to help determine a proper management plan. This paper reviews the existing state of the art of predictive modeling for bronchiolitis. Predictive modeling for respiratory syncytial virus (RSV) infection is covered whenever appropriate, as RSV accounts for about 70% of bronchiolitis cases.Methods: A systematic review was conducted through a PubMed search up to April 25, 2014. The literature on predictive modeling for bronchiolitis was retrieved using a comprehensive search query, which was developed through an iterative process.Search results were limited to human subjects, the English language, and children (birth-18 years). Results:The literature search returned 2,312 references in total. After manual review, 168 of these references were determined to be relevant and are discussed in this paper. We identify several limitations and open problems in predictive modeling for bronchiolitis, and provide some preliminary thoughts on how to address them, with the hope to stimulate future research in this domain. Conclusions:Many problems remain open in predictive modeling for bronchiolitis. Future studies will need to address them to achieve optimal predictive models.

show abstract

International variation in the management of infants hospitalized with respiratory syncytial virus

Cited by 179 publications

References 9 publications

Racial/Ethnic differences in the presentation and management of severe bronchiolitis

Racial/Ethnic differences in the presentation and management of severe bronchiolitis

Prevalência de sibilância e fatores associados em crianças indígenas Guarani hospitalizadas por doença respiratória aguda no Sul e Sudeste do Brasil

A systematic review of predictive modeling for bronchiolitis

Contact Info

Product

Resources

About