Peer support is an important component of client-centered care. However, there are numerous barriers faced by traditional peer support delivery that have limited its role, such as timeliness and location of service. Smartphone technology may provide a cost-effective mode of delivery that overcomes many such barriers, offering immediate and accessible service. Such a mobile application may play a role in alleviating experiences of distress. This paper reviews literature relevant to the use of mobile applications in peer support. Investigators conducted an integrative literature review utilizing online databases and triangulation. No literature evaluating the use of mobile application in peer support was discovered. As such, investigators included literature regarding the efficacy of technology-based peer support and the efficacy of health intervention through mobile applications. These studies highlighted both the health outcomes associated with peer support and the limitations specific to mobile application healthcare interventions. Of note, these limitations include the intergenerational gap in use of mobile applications, as well as ethical and privacy considerations. Findings suggest that a mobile application for peer support may provide effective intervention for distress, in turn alleviating stress on other healthcare system resources. Peer support delivered in this manner should complement and not replace the usual face-toface support or direct crisis intervention.