2010
DOI: 10.1016/j.ijbiomac.2010.07.009
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Interpenetrating network hydrogel membranes of sodium alginate and poly(vinyl alcohol) for controlled release of prazosin hydrochloride through skin

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Cited by 141 publications
(65 citation statements)
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References 25 publications
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“…Solpan et al prepared semi-IPN of sodium alginate and acrylamide and used this hydrogel for separation of several textile dyes from water (Dilek, Murat, & Guven, 2008). Kulkarni et al synthesized IPN of polyvinyl alcohol and sodium alginate and used it for controlled release of prazosin hydrochloride from skin (Kulkarni, Sreedhara, Mutalikb, Setty, & Sa, 2010). Wang and Wang grafted sodium alginate with sodium acrylate and prepared semi-IPN with this grafted copolymer and polyvinyl pyrolidone.…”
Section: Introductionmentioning
confidence: 99%
“…Solpan et al prepared semi-IPN of sodium alginate and acrylamide and used this hydrogel for separation of several textile dyes from water (Dilek, Murat, & Guven, 2008). Kulkarni et al synthesized IPN of polyvinyl alcohol and sodium alginate and used it for controlled release of prazosin hydrochloride from skin (Kulkarni, Sreedhara, Mutalikb, Setty, & Sa, 2010). Wang and Wang grafted sodium alginate with sodium acrylate and prepared semi-IPN with this grafted copolymer and polyvinyl pyrolidone.…”
Section: Introductionmentioning
confidence: 99%
“…As the concentration of Ca 2+ was increased, we observed decrease in drug release rate. It can be ascribed to the fact that at higher crosslinking, free-volume of matrix decreases, so delaying the diffusion of drug through microbeads [33]. It is also observed that the increased amount of PAAm-g-GG has resulted in decreased drug release.…”
Section: In Vitro Dissolution Studymentioning
confidence: 99%
“…6 Consequently, −COO − , which dissociates from SA, is associated with H þ , and turns into −COOH in strong acidic mediums with a pH value of 0 to 2, as shown in Fig. Molecular chains of SA contain lots of carboxyl, while the ionization of carboxyl is related to the pH environment.…”
Section: Principles Of Swellingmentioning
confidence: 99%