Interplay of electronic and geometric structure on Cu phenanthroline, bipyridine and derivative complexes, synthesis, characterization, and reactivity towards oxygen

Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug mechanisms

“…In biological systems, copper is known to easily transition between the +1 and +2 oxidation states. 134 Typically, the redox activity of copper complexes and the production of reactive oxygen species serve as the basis for their mode of action. 135 Copper is redox-active and cycles between the +1 and +2 oxidative states when bound to amyloid beta (Aβ) proteins.…”

Connectivity Defects in Metallo-Supramolecular Polymer Networks at Different Self-Sorting Regimes

“…Dissolved oxygen can react with Cu + ions and oxidize them to Cu 2+ . The reaction of Cu + complexes with oxygen has been widely studied, giving evidence for the formation of oxygen adducts as intermediates, whose low stability favors the generation of reactive oxygen species as final products, like hydroxyl radicals and hydrogen peroxide. , However, it has been reported that the electron configuration in Cu + complexes usually forces a tetrahedral geometry, whereas square planar and even square pyramidal are commonly found for Cu 2+ compounds. Phenanthroline derivatives like 2,9-substituted ones tend to enforce the tetrahedral coordination geometry due to steric demand and therefore provide potential for reduction of Cu 2+ to Cu + .…”

Rich or poor: the impact of electron donation and withdrawal on the photophysical and photocatalytic properties of copper(i) complexes

“…27,[29][30][31][32][33] Among the first row, copper(I) complexes show some unique properties due to its closed shell d 10 electron configuration and the great diversity in possible ligand design. 17,31,[34][35][36][37][38][39] In particular, heteroleptic diimine-diphosphine copper(I) complexes of the type [Cu(N^N)(P^P)] + (Fig. 1) came into focus due to their long excited state lifetimes, beneficial excited state potentials and broad tunability.…”

“…1 O 2 is used, for example, in the photodynamic therapy of cancer and in synthetic chemistry as a strong oxidant. 39,[52][53][54] To demonstrate the applicability of the PSs in this context, the catalytic photooxygenation of 2,5-diphenylfuran (DPF) to cis-dibenzoyl ethylene (DBE) 52,[55][56][57] was chosen as a model reaction.…”