Interpregnancy Weight Change and Risk for Adverse Perinatal Outcome

Bogaerts, Annick; Bergh, Bea Van den; Ameye, Lieveke; Witters, Ingrid; Martens, Evelyne; Timmerman, Dirk; Devlieger, Roland

doi:10.1097/aog.0b013e3182a7f63e

Cited by 135 publications

(162 citation statements)

References 33 publications

Supporting

Mentioning

148

Contrasting

Unclassified

Order By: Relevance

“…If a mother is delivered early to prevent complications of pre‐eclampsia, the risk of maternal mortality may be lowered but that of offspring mortality is increased as a result of prematurity. Addressing this issue requires the simultaneous assessment of both outcomes in the same cohort, and the one study that did this had a small sample size of just 7897, risking imprecision and overfitting 6. These deficiencies threaten the validity of the findings in the literature and their current applicability, as reproductive behaviour and outcomes have changed considerably over time.…”

Section: Introductionmentioning

confidence: 99%

Interpregnancy interval and perinatal outcomes across Latin America from 1990 to 2009: a large multi‐country study

Mignini

Carroli

Betrán

et al. 2015

BJOG

View full text Add to dashboard Cite

ObjectiveTo determine the relationship of interpregnancy interval with maternal and offspring outcomes.DesignRetrospective study with data from the Perinatal Information System database of the Latin American Centre for Perinatology and Human Development, Uruguay.SettingLatin America, 1990–2009.PopulationA cohort of 894 476 women delivering singleton infants.MethodsDuring 1990–2009 the Perinatal Information System database of the Latin American Centre for Perinatology identified 894 476 women with defined interpregnancy intervals: i.e. the time elapsed between the date of the previous delivery and the first day of the last normal menstrual period for the index pregnancy. Using the interval 12–23 months as the reference category, multiple logistic regression estimated adjusted odds ratios (aORs) with 95% confidence intervals (95% CIs) of the association between various interval lengths and maternal and offspring outcomes.Main outcome measuresMaternal death, pre‐eclampsia, eclampsia, puerperal infection, fetal death, neonatal death, preterm birth, and low birthweight.ResultsIn the reference interval there was 0.05% maternal death, 1.00% postpartum haemorrhage, 2.80% pre‐eclampsia, 0.15% eclampsia, 0.28% puerperal infection, 3.45% fetal death, 0.68% neonatal death, 12.33% preterm birth, and 9.73% low birthweight. Longer intervals had increased odds of pre‐eclampsia (>72 months), fetal death (>108–119 months), and low birthweight (96–107 months). Short intervals of <12 months had increased odds of pre‐eclampsia (aOR 0.80; 95% CI 0.76–0.85), neonatal death (aOR 1.18; 95% CI 1.08–1.28), and preterm birth (aOR 1.16; 95% CI 1.11–1.21). Statistically, the interval had no relationship with maternal death, eclampsia, and puerperal infection.ConclusionsA short interpregnancy interval of <12 months is associated with pre‐eclampsia, neonatal mortality, and preterm birth, but not with other maternal or offspring outcomes. Longer intervals of >72 months are associated with pre‐eclampsia, fetal death, and low birthweight, but not with other maternal or offspring outcomes.Tweetable abstractA short interpregnancy interval of <12 months is associated with neonatal mortality and preterm birth.

show abstract

Section: Introductionmentioning

confidence: 99%

Interpregnancy interval and perinatal outcomes across Latin America from 1990 to 2009: a large multi‐country study

Mignini

Carroli

Betrán

et al. 2015

BJOG

View full text Add to dashboard Cite

show abstract

“…Even in a normal range of BMI, a prepregnancy weight gain has been associated with an elevated risk of GDM [12,14]. Weight gain/retention between consecutive pregnancies has also been found to be linked with the increased risk of GDM [14,15]. However, the existing scarce studies were limited to nursing professional mothers whose childhood body shape and weight (at 18 years) were reported retrospectively and subsequent adult weights were collected over a short interval [12].…”

Section: Introductionmentioning

confidence: 99%

“…However, the existing scarce studies were limited to nursing professional mothers whose childhood body shape and weight (at 18 years) were reported retrospectively and subsequent adult weights were collected over a short interval [12]. The other studies collected weight trajectories in a single retrospective interview [11] or measured only inter-pregnancy weight change [14,15] rather than over the life course. These studies were further limited to clinical populations and lacked adjustment for potential confounders such as diet, and physical activity, a fact acknowledged by the authors [11].…”

Section: Introductionmentioning

confidence: 99%

Pre-pregnancy weight change and incidence of gestational diabetes mellitus: A finding from a prospective cohort study

Adane

Tooth

Mishra

2017

Diabetes Research and Clinical Practice

View full text Add to dashboard Cite

Aims: In a population-based cohort study we examined the associations between early adult pre-pregnancy weight change and the risk of gestational diabetes mellitus (GDM). Methods:The study included 3,111 women from the 1973-78 cohort of the Australian Longitudinal Study on Women's Health. These women have been surveyed regularly since 1996. Women without diabetes and GDM were followed-up between 2003 and 2012.Generalized estimating equations were used to assess the effect of baseline (1996, mean age 20 years) and pre-pregnancy body mass index (BMI) and the pre-pregnancy weight changes on the incidence of GDM. The full models were adjusted for sociodemographic and lifestyle factors.Results: From 2003-2012, 229 GDM cases (4.4%) were reported in 5,242 pregnancies.Relative to normal BMI women, obese women at baseline (RR: 1.8, 95% CI: 1.1, 2.8) and prior to pregnancy (RR: 2.7, 95% CI: 2.0, 3.6) were at greater risk of GDM. Weight gains prior to each study pregnancy were strongly associated with increased GDM risk with an adjusted RR ranging from 2.0 to 2.9. Within under/normal range of BMI, women with a moderate/high (>2.5%/year) weight gain had 2.7 (95% CI: 1.3, 5.5) times the risk of GDM compared with women with stable weight. Conclusions:Early adult weight gain, even within normal BMI range, is an important risk factor for the development of GDM. Weight gain prevention from early adulthood to prior to pregnancy appears to be the main strategy to prevent the incidence of GDM.

show abstract

“…Further, excessive GWG is associated with postpartum weight retention, which is an important indicator of obesity in midlife (19). Maternal weight retention between the first and second pregnancies is also associated with adverse pregnancy outcomes in the following pregnancy, even in normal weight women (20). Inadequate GWG is associated with small for gestational age and preterm birth (21).…”

Section: Gestational Weight Gainmentioning

confidence: 99%

Maternal obesity, duration of labor and the role of leptin

Carlhäll¹

2018

Linköping University Medical Dissertations

View full text Add to dashboard Cite

Background: The prevalence of obesity substantially increases in pregnant women. Maternal obesity is associated with adverse maternal and neonatal outcomes. The increased risk for cesarean section present in obese women has been related to potential impaired uterine contractility. The mechanism that underlies this theory is not clear. In vitro studies have shown that leptin, produced by adipose tissue and the placenta, exerts an inhibitory effect on myometrial contractility. The aim of this thesis was to evaluate the labor process in relation to maternal body mass index (BMI) and the clinical role of leptin in this process.

show abstract

Interpregnancy Weight Change and Risk for Adverse Perinatal Outcome

Abstract: II.

Cited by 135 publications

References 33 publications

Interpregnancy interval and perinatal outcomes across Latin America from 1990 to 2009: a large multi‐country study

Interpregnancy interval and perinatal outcomes across Latin America from 1990 to 2009: a large multi‐country study

Pre-pregnancy weight change and incidence of gestational diabetes mellitus: A finding from a prospective cohort study

Maternal obesity, duration of labor and the role of leptin

Contact Info

Product

Resources

About