Interpretation of the potential response of PVC membrane ion-selective electrodes based on the mixed potential theory

Osakai, Toshiyuki; Sato, Yohei; Imoto, Maya; Sakaki, Takeshi

doi:10.1016/j.jelechem.2012.01.019

Cited by 4 publications

(12 citation statements)

References 24 publications

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“…Recently, a PVC membrane DES + -ISE was developed by Gupta et al, 11 who designed it in a conventional screening procedure. In this paper, we have employed a micro PVC membrane/water (W) interface 4 to study the interfacial transfer of protonated forms of DES and its analogues, including imipramine (IMP) and neostigmine (NEO) (also see Fig. 1).…”

Section: Original Papersmentioning

confidence: 99%

“…PVC (degree of polymerization = 1100, Wako) was purified as described previously. 4 ο-Nitrophenyl octyl ether (NPOE; ≥99%) was purchased from Dojindo Laboratories and used as received.…”

Section: Chemicalsmentioning

confidence: 99%

“…As reported previously, 4 a micro PVC membrane/W interface was formed by pressing the end of a glass pipette (ca. 100 μm i.d.)…”

Section: Voltammetrymentioning

confidence: 99%

“…So far, a large number of polymer membrane ISEs have been developed for many ions; [1][2][3] however, the design of ISEs is usually by screening or trial-and-error, i.e., by changing the membrane components and their concentrations in a systematic manner. In a preceding paper, 4 we showed that the mixed-potential (MP) theory proposed by Kakiuchi and Senda 5 and Kihara and Yoshida 6 is useful for understanding the potential response not only of unsupported liquid membrane ISEs, but also of polyvinyl chloride (PVC) supported liquid membrane ISEs. The MP theory 5,6 is based on the concept of a zero-current potential of the interface between the unsupported or supported liquid membrane and a sample solution containing interfering ions.…”

Section: Introductionmentioning

confidence: 99%

“…Kakiuchi and Senda 5 also showed that the selectivity coefficients of the ISEs could be expressed as a function of the difference between the standard ion-transfer potentials of the primary and interfering ions, the ratios of the mass-transfer coefficients of the ions, and the ratios of their concentrations. In our preceding paper, 4 the potential response of an ion exchanger-type PVC membrane ISE for tetraethylammonium (TEA + ) ion was successfully explained by MP theory.…”

Section: Introductionmentioning

confidence: 99%

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Application of the Mixed-Potential Theory to the Interpretation of the Potential Response of a PVC Membrane Ion-Selective Electrode for Desipramine

et al. 2012

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The potential response of an ion-exchanger type PVC ion-selective electrode (ISE) for a drug ion, desipramine(+) (DES(+)), was analyzed by a mixed-potential (MP) theory proposed previously. The transfer of DES(+) and its analogous ions, imipramine(+) (IMP(+)) and neostigmine(+) (NEO(+)), at a micro Ο-nitrophenyl octyl ether/water interface was studied by ion-transfer voltammetry; also, the standard ion-transfer potentials (Δ(O)(W)φ(j)(o)) of the ions were then determined. The application of MP theory with the Δ(O)(W)φ(j)(o) values successfully explained the under-Nernstian response of DES(+)-ISE due to interference from IMP(+) or NEO(+). In this study, a universal method based on numerical calculations was developed for evaluating MP associated with plural interfering ions, which was impossible in the previous method based on analytical equations. Using the universal method, we could well predict the detection limit of DES(+)-ISE theoretically. The MP theory is promising for the sophisticated design of ISEs, which is not due to conventional "trial-and-error" procedures.

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Section: Original Papersmentioning

confidence: 99%

“…PVC (degree of polymerization = 1100, Wako) was purified as described previously. 4 ο-Nitrophenyl octyl ether (NPOE; ≥99%) was purchased from Dojindo Laboratories and used as received.…”

Section: Chemicalsmentioning

confidence: 99%

“…As reported previously, 4 a micro PVC membrane/W interface was formed by pressing the end of a glass pipette (ca. 100 μm i.d.)…”

Section: Voltammetrymentioning

confidence: 99%