"Interstitial Lung disease (Ild) in Rheumatoid arthritis (Ra)"- a study of thirty cases

Raniga, Sameer; Sharma, Pranav; Kaur, Gagandeep; Arora, Arushi; Khalasi, Y; Vohra, PV

doi:10.4103/0971-3026.32362

Cited by 14 publications

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“…The prevalence of restrictive PFT abnormality was more common in female patients. However, the prevalence of ILD and pleural involvement that causes restriction is more common in men a study conducted by Gabbay et al 8 Majority of patients with PFT abnormality in this study were in the fifth and sixth decades which was similar to a study by Raniga et al 9 and Fuld et al 10 PFTs were more sensitive in detecting pulmonary abnormalities than chest radiographs. However, when both these investigations were used together, the yield of pulmonary abnormalities was better than either test alone.…”

Section: Discussionsupporting

confidence: 86%

A Comparative Study of Pulmonary Function Test Abnormalities in Rheumatoid Arthritis-Treatment Naive Versus Patients on Treatment

Dakshinamoorthy¹,

Azhaganantham²

2018

jemds

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BACKGROUND Rheumatoid Arthritis (RA) is a chronic systemic inflammatory disease characterized by persistent synovitis of most of the peripheral joints. Pulmonary involvement is one of the important extra articular features of RA with worse prognosis. Current research aimed to compare the pulmonary function test abnormalities in RA patients-treatment naïve versus patients on treatment. MATERIALS AND METHODS 50 rheumatoid arthritis patients were divided into two groups-treatment naïve group & on treatment group and evaluated for lung involvement by spirometry. Those patients showing lung function abnormalities were evaluated for correlation with various characteristics like age, gender, duration of treatment, pattern of PFT abnormality and the severity of arthritis. RESULTS PFT abnormalities were found in more than half of RA patients with restrictive pattern of lung disease being the commonest abnormality in females. There is increased prevalence of PFT abnormality in 'on treatment' group when compared to treatment naïve group. CONCLUSION Lung involvement is one of the most important extraarticular manifestations of rheumatoid arthritis. Pulmonary function test (PFT) helps in identifying the lung involvement and its pattern in rheumatoid arthritis patients.

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Section: Discussionsupporting

confidence: 86%

A Comparative Study of Pulmonary Function Test Abnormalities in Rheumatoid Arthritis-Treatment Naive Versus Patients on Treatment

Dakshinamoorthy¹,

Azhaganantham²

2018

jemds

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“…While ILD cases ultimately require referral to a pulmonologist, many cases can be diagnosed in the early stages with the help of HRCT. [25][26][27] HRCT is able to detect abnormalities in patients when the clinical signs are minimal or even when the chest radiograph appears completely normal. confident diagnosis can often be arrived at by HRCT alone or in correlation with the clinical symptoms.…”

Section: Discussionmentioning

confidence: 99%

Assessment of high resolution computed tomography in the diagnosis of interstitial lung disease

Ayush¹,

Jakhanwal²

2018

Int J Res Med Sci

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Background: Interstitial lung disease (ILD) are group of pulmonary disorders characterized by inflammation and fibrosis of gas exchanging portion of the lung and diffuse abnormalities on lung radiograph. Conventional computerized tomography plays a limited role in evaluation of interstitial lung disease due to its inability to demonstrate fine parenchymal details. High Resolution Computed Tomography (HRCT) is currently the most accurate non invasive modality for evaluating lung- parenchyma. So, the purpose of the study was to assess high resolution computed tomography in the diagnosis of interstitial lung disease.Methods: 50 patients with clinical suspicion of interstitial lung disease who were referred to Department of Radio-Diagnosis and Imaging for diagnosis and evaluation were subjected to both conventional radiography and HRCT.Results: Majority of the cases i.e. 9 (18%) had honeycombing, 8 (16%) cases had crazy paving pattern and mosaic attenuation, 7 (14%) cases had miliary mottling, 6 (12%) cases had normal, 5 (10%) cases had fibrosis and ground glass haze, 2 (4%) cases had ground glass haze with Intralobular reticular opacities and 2 (4%), subpleural nodular opacities and 2 (4%) cases had B/lHilar lymphadenopathy.Conclusions: Ultimately all patients with clinical suspicion of ILDs should benefit from an HRCT scan of the thorax. High resolution computed tomography (HRCT) chest scans are essential to the diagnostic work-up since each ILD form is characterized by a specific pattern of abnormalities and a confident diagnosis can often be arrived at by HRCT alone or in correlation with the clinical symptoms. When HRCT findings are characteristic in appropriate clinical settings, HRCT may even obviate the need for a lung biopsy.

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“…HRCT can show evidence of interstitial lung changes even when clinical and pulmonary function tests are normal. HRCT is superior to plain chest radiograph in the evaluation of early interstitial lung changes associated with RA [12].…”

Section: Discussionmentioning

confidence: 99%

High resolution computed tomography in the evaluation of interstitial lung diseases: Imaging perspective revisited with review of literature

Gupta¹,

Kashmir²,

Ilyas³

et al. 2017

Int J Med Res Rev

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Aims and Objectives: The study was designed with a broad objective of studying the imaging findings of the common interstitial lung diseases and to assess the severity of the disease and determine the reversibility capability of the pulmonary parenchymal damage in ILD's. Patients and Methods: This was a prospective, observational study in which we evaluated 50 patients suspected of having interstitial lung diseases based on radiographic or clinical findings, by high resolution computed tomography (HRCT) over a period of one year. Results: Out of the 50 patients, majority of them had idiopathic pulmonary fibrosis (n=16) followed by interstitial pulmonary involvement in patients of rheumatoid arthritis (n=13), scleroderma (n=10) and systemic lupus erythematosis (n=9). The less common ILD's included were Occupational lung disease (n=1) and Mycosis fungoides (n=1). Conclusion: HRCT of the lung in cases of the suspected interstitial lung diseases forms an invaluable tool for accurate and early identification and in conjunction with the clinical findings can obviate the need of lung biopsy in diagnosis of ILD's. ……………………………………………………………………………………………………………………………….

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"Interstitial Lung disease (Ild) in Rheumatoid arthritis (Ra)"- a study of thirty cases

Cited by 14 publications

References 0 publications

A Comparative Study of Pulmonary Function Test Abnormalities in Rheumatoid Arthritis-Treatment Naive Versus Patients on Treatment

A Comparative Study of Pulmonary Function Test Abnormalities in Rheumatoid Arthritis-Treatment Naive Versus Patients on Treatment

Assessment of high resolution computed tomography in the diagnosis of interstitial lung disease

High resolution computed tomography in the evaluation of interstitial lung diseases: Imaging perspective revisited with review of literature

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