Interventions to Improve Medication Adherence

Kini, Vinay; Ho, P. Michael

doi:10.1001/jama.2018.19271

Cited by 407 publications

(339 citation statements)

References 82 publications

Supporting

Mentioning

316

Contrasting

Unclassified

Order By: Relevance

“…In practice, this translates to a risk of accumulation of leftover antibiotics and excess drug waste presented as either antibiotic or PPI. Furthermore, it is well‐established that patient compliance is inversely related to the number of drugs that the patient it taking . Previous research indicates that leftover antibiotics may contribute to inappropriate antibiotic consumption hence further promoting antibiotic resistance .…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, it is well-established that patient compliance is inversely related to the number of drugs that the patient it taking. [13][14][15] Previous research indicates that leftover antibiotics may contribute to inappropriate antibiotic consumption hence further promoting antibiotic resistance. 6 Drug waste may also contribute to antibiotic resistance and raise healthcare cost.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Correlation of registered drug packs with Maastricht V/Florence Consensus Report and national treatment guidelines for management of Helicobacter pylori infection

Jukic

Rušić

Vuković

et al. 2019

Basic Clin Pharma Tox

View full text Add to dashboard Cite

High prevalence of Helicobacter pylori infection, the complexity for its treatment, poor correlation of registered drug packs or poor patient adherence to the treatment may contribute to antibiotic resistance and healthcare costs. The aim of the present study was to investigate whether registered drug packs are in accordance with European and national guidelines for H pylori eradication with reference to the number of drug units. In this study, we considered treatment options for the management of H pylori infection recommended by the Maastricht V/Florence Consensus Report and by national guidelines in the United Kingdom (UK), Croatia, Italy and Slovenia for adults. Drugs proposed by the guidelines were identified in national drug databases in July of 2019. When considering correlation for 10‐day treatment regimens, drug packs registered in Croatia could not be matched with recommendations for sequential therapies. A number of proposed treatments could not be matched due to small variety of drug packs in Croatia. Drug packs registered in the UK more often matched recommended 14‐day treatment regimens and national guidelines. With reference to European guidelines, 10‐day treatments could more frequently be matched in Italy and in Slovenia. Furthermore, results of this study indicate that there is smaller variety in drug pack sizes registered in Croatia and Slovenia when compared to UK and Italy. Considering poor correlation of drug packs with treatment guidelines for H pylori, adherence to antimicrobial treatment and proper disposal of antimicrobials is warrant. Discussing adherence to antimicrobial treatment with patients should be introduced as a standard of patient care and education.

show abstract

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

Correlation of registered drug packs with Maastricht V/Florence Consensus Report and national treatment guidelines for management of Helicobacter pylori infection

Jukic

Rušić

Vuković

et al. 2019

Basic Clin Pharma Tox

View full text Add to dashboard Cite

show abstract

“…Secondly, our experience shows the importance of organisational aspects in the RPMS context. While the full potential of e-health technologies to improve care coordination is often put forward, published data tends to show that additional investment is required to develop closer human relationships, as evidenced in a recent analysis of intervention programmes leading to improved medical compliance (45). This was consistent with the feelings of clinicians and patients who insisted on the fact that the technological tool is only a support mechanism and should not replace personal contact with health professionals or patients -a point already made elsewhere (46,47).…”

Section: Discussionmentioning

confidence: 99%

How to Design a Remote Patient Monitoring System A French Case Study

Ferrua

Minvielle

Fourcade

et al. 2020

Preprint

View full text Add to dashboard Cite

Background Remote Patient Monitoring Systems (RPMS) based on e-health, Nurse Navigators (NNs) and patient engagement can improve patient follow-up and have a positive impact on quality of care (by limiting adverse events) and costs (by reducing readmissions). However, the extent of this impact depends on effective implementation which is often restricted. This is partly due to the lack of attention paid to the RPMS design phase prior to implementation. The content of the RPMS can be carefully designed at this stage and various obstacles anticipated. Our aim was to report on an RPMS process design to provide an insight into the methodology required in order to manage this phase and the ultimate outcome in terms of RPMS content. Methods This study was carried out at Gustave Roussy, a comprehensive cancer centre in France. A multidisciplinary team comprising hospital managers, healthcare professionals and health service researchers coordinated the CAPRI RPMS design process (2013-2015). It is based on data collected during eight studies conducted in accordance with the principle framework of the UK Medical Research Council (MRC). This project was approved by the French National Data Protection Authorities. Results Based on the study results, the multidisciplinary team defined strategies for resolving obstacles and risks prior to the implementation of CAPRI. Consequently, the final CAPRI design includes a web app with two interfaces (patient and health care professionals) and two NNs. The NNs provide regular follow-up via telephone and/or email to manage patients' symptoms and toxicity, treatment compliance and care packages. Patients contact the NNs via a secure messaging system. Eighty graduation and orientation algorithms enable NNs to prioritise and decide on the course of action to be taken. Conclusion In our experience, the RPMS design process and, more generally, that of any complex intervention programme, is an important phase that requires a sound methodological basis. This study also suggests that an RPMS is more than a technological innovation. Indeed, it is an organisational innovation, the merits of which will depend on the precise definition given to the action taken by NNs and other healthcare professionals as well as patients throughout their interactions.

show abstract

“…In the United States, medication nonadherence is responsible for ≈125 000 deaths, 10% of hospitalizations, and $100 billion in health care services annually . To address this issue, Proteus Digital Health, Inc. developed a medication adherence monitoring system where an ingestible sensor transmits its identification code to a wearable receiver patch upon contact with gastric fluid (see Figure c) .…”

Section: Ingestible Robots For Drug Deliverymentioning

confidence: 99%

Robotics in the Gut

Min

Yang

et al. 2019

Advanced Therapeutics

View full text Add to dashboard Cite

Since the advent of ingestible temperature sensors and capsule endoscopes, rapid advances in electronics, robotics, nanotechnology, and material sciences have opened the door for the development of novel medical ingestible robots. The untethered robots provide direct, non-invasive access to the entire gastrointestinal (GI) tract. Furthermore, the tissues, gases, and fluids of the gastrointestinal lumen contain a multitude of biomarkers indicative of gut diseases and health. Ingestible medical robots equipped with advanced imaging and sensing techniques can enable the diagnosis and monitoring of diseases, while providing a better pathophysiological understanding of gastrointestinal disorders. In addition, various robotic actuation mechanisms in the macro-and microscale can realize enhanced drug delivery and surgical interventions for the treatment of diseases. In this paper, an overview of recent advances in ingestible robots toward imaging, sensing, drug delivery, and surgical applications in the GI tract is provided. Key challenges and strategies for the development of novel ingestible robots and future directions of ingestible robots toward precision medicine are also discussed.

show abstract

Interventions to Improve Medication Adherence

Abstract: IMPORTANCE Among adults with chronic illness, 30% to 50% of medications are not taken as prescribed. In the United States, it is estimated that medication nonadherence is associated with 125 000 deaths, 10% of hospitalizations, and $100 billion in health care services annually.

Cited by 407 publications

References 82 publications

Correlation of registered drug packs with Maastricht V/Florence Consensus Report and national treatment guidelines for management of Helicobacter pylori infection

Correlation of registered drug packs with Maastricht V/Florence Consensus Report and national treatment guidelines for management of Helicobacter pylori infection

How to Design a Remote Patient Monitoring System A French Case Study

Robotics in the Gut

Contact Info

Product

Resources

About