Interventions to increase tuberculosis case detection at primary healthcare or community level services

Mhimbira, Francis; Cuevas, Luís E.; Dacombe, Russell; Mkopi, Abdallah; Sinclair, David

doi:10.1002/14651858.cd011432

Cited by 4 publications

(1 citation statement)

References 10 publications

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“…в стране не существует системы профилактики и скрининга туберкулеза [11]. Однако систематический обзор, опубликованный в 2017 г., с анализом 17 рандомизированных контролируемых исследований показал высокую эффективность «активного» подхода к диагностике туберкулеза именно в условиях высокой распространенности туберкулеза на территории Индии [12].…”

Section: результатыunclassified

Organization of tuberculosis detection in Russia and worldwide

Borodulina¹,

Суслин²

2018

Profil. med.

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Своевременное выявление туберкулеза является важнейшим мероприятием, препятствующим распространению туберкулезной инфекции среди населения, повышающим вероятность благоприятного исхода лечения больных. Проанализированы результаты зарубежных и отечественных оригинальных исследований по вопросам организации выявления туберкулеза за период 2010-2018 гг., представленные в базах медицинских и биологических публикаций PubMed и Elibrary, также изучены данные ежегодных докладов ВОЗ по туберкулезу. Представлены данные для стран-лидеров организации БРИКС, где сложилась напряженная обстановка по туберкулезу, и для эпидемиологически благополучных стран с низкой заболеваемостью (Великобритания, Австралия, США).

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Section: результатыunclassified

Organization of tuberculosis detection in Russia and worldwide

Borodulina¹,

Суслин²

2018

Profil. med.

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Interventions to increase tuberculosis case detection at primary healthcare or community-level services

Mhimbira

Cuevas

Dacombe

et al. 2017

Cochrane Database of Systematic Reviews

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BackgroundPulmonary tuberculosis is usually diagnosed when symptomatic individuals seek care at healthcare facilities, and healthcare workers have a minimal role in promoting the health-seeking behaviour. However, some policy specialists believe the healthcare system could be more active in tuberculosis diagnosis to increase tuberculosis case detection.ObjectivesTo evaluate the effectiveness of different strategies to increase tuberculosis case detection through improving access (geographical, financial, educational) to tuberculosis diagnosis at primary healthcare or community-level services.Search methodsWe searched the following databases for relevant studies up to 19 December 2016: the Cochrane Infectious Disease Group Specialized Register; the Cochrane Central Register of Controlled Trials (CENTRAL), published in the Cochrane Library, Issue 12, 2016; MEDLINE; Embase; Science Citation Index Expanded, Social Sciences Citation Index; BIOSIS Previews; and Scopus. We also searched the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP), ClinicalTrials.gov, and the metaRegister of Controlled Trials (mRCT) for ongoing trials.Selection criteriaRandomized and non-randomized controlled studies comparing any intervention that aims to improve access to a tuberculosis diagnosis, with no intervention or an alternative intervention.Data collection and analysisTwo review authors independently assessed trials for eligibility and risk of bias, and extracted data. We compared interventions using risk ratios (RR) and 95% confidence intervals (CI). We assessed the certainty of the evidence using the GRADE approach.Main resultsWe included nine cluster-randomized trials, one individual randomized trial, and seven non-randomized controlled studies. Nine studies were conducted in sub-Saharan Africa (Ethiopia, Nigeria, South Africa, Zambia, and Zimbabwe), six in Asia (Bangladesh, Cambodia, India, Nepal, and Pakistan), and two in South America (Brazil and Colombia); which are all high tuberculosis prevalence areas.Tuberculosis outreach screening, using house-to-house visits, sometimes combined with printed information about going to clinic, may increase tuberculosis case detection (RR 1.24, 95% CI 0.86 to 1.79; 4 trials, 6,458,591 participants in 297 clusters, low-certainty evidence); and probably increases case detection in areas with tuberculosis prevalence of 5% or more (RR 1.52, 95% CI 1.10 to 2.09; 3 trials, 155,918 participants, moderate-certainty evidence; prespecified stratified analysis). These interventions may lower the early default (prior to starting treatment) or default during treatment (RR 0.67, 95% CI 0.47 to 0.96; 3 trials, 849 participants, low-certainty evidence). However, this intervention may have may have little or no effect on treatment success (RR 1.07, 95% CI 1.00 to 1.15; 3 trials, 849 participants, low-certainty evidence), and we do not know if there is an effect on treatment failure or mortality. One study investigated long-term prevalence in the community, but with no clea...

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Protocol for a qualitative synthesis of barriers and facilitators in implementing guidelines for diagnosis of tuberculosis

et al. 2017

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IntroductionDespite the introduction of new tests and guidelines for diagnosis of tuberculosis (TB), worldwide case detection rate of TB is still suboptimal. This could be in part explained by the poor implementation of TB diagnostic guidelines. We aim to identify, appraise and synthesise qualitative evidence exploring the barriers and facilitators to implementing TB diagnostic guidelines.Methods and analysisA systematic review of qualitative studies will be conducted. Relevant electronic databases will be searched and studies included based on predefined inclusion criteria. We will also search reference lists, grey literature, conduct forward citation searches and contact relevant content experts. An adaptation of the Critical Appraisal Skills Programme tool will be used to assess the methodological quality of included studies. Two authors will review the search output, extract data and assess methodological quality independently, resolving any disagreements by consensus. We will use the thematic framework analysis approach based on the Supporting the Use of Research Evidence thematic framework to analyse and synthesise our data. We will apply the Confidence in the Evidence from Reviews of Qualitative research approach to transparently assess our confidence in the findings of the systematic review.Ethics and disseminationThis protocol has been registered with the International Prospective Register of Systematic Reviews (PROSPERO), registration number CRD42016039790Trial registration numberPROSPERO 2016: CRD42016039790. Available from http://www.crd.york.ac.uk/PROSPERO/

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Interventions to increase tuberculosis case detection at primary healthcare or community level services

Cited by 4 publications

References 10 publications

Organization of tuberculosis detection in Russia and worldwide

Organization of tuberculosis detection in Russia and worldwide

Interventions to increase tuberculosis case detection at primary healthcare or community-level services

Protocol for a qualitative synthesis of barriers and facilitators in implementing guidelines for diagnosis of tuberculosis

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