Intestinal anti-inflammatory activity of Ulva ohnoi oil in DSS-induced experimental mouse model

Abstract

This study was conducted to examine the physiological activity of Ulva ohnoi, some of which may be used for food or natural products but could disturbing coastal ecosystems due to large scale green-tide, to check values of U. ohnoi oil through experimental results. U. ohnoi oil was extracted from bulk of Ulva biomass to confirm its antioxidant and antibacterial activity, and the efficacy of U. ohnoi oil in the state of inflammation was confirmed through animal experiments. To confirm the anti-inflammatory effect, a mouse model induced with DSS was used. As a result of measuring NO using plasma after induction of inflammation, the amount of NO produced in the U. ohnoi oil group was decreased compared to the control group. Expression of inflammatory cytokines TNF-α, IL-6, and IL-1β was decreased compared to the control group. As a result of observing H&E staining, lower crypt loss and inflammatory cell infiltration were found in the U. ohnoi oil group compared to the control group. Consequently, U. ohnoi oil appears to have great anti-inflammatory properties.

Biocompounds from Green Algae of Romanian Black Sea Coast as Potential Nutraceuticals

“…Sulphated polysaccharide and oligosaccharide biocompounds generate important biological activities such as anti-inflammatory, antidiabetic, antiobesity, immunomodulatory, antioxidant, antitumoral, antimicrobial activities, as reported by Liu et al for green algae from marine water from China and by Kang et al for green algae from the coastal waters of Korea. [73,74]. In this study, as shown in Figure 4 and Table 6, the lipid content in algae was in the following ascending order: the lowest in Enteromorpha intestinalis, followed by Ulva lactuca, and highest in Cladophora vagabunda.…”

Solea senegalensis Bacterial Intestinal Microbiota Is Affected by Low Dietary Inclusion of Ulva ohnoi

“…Although different Ulva species have been applied in several areas, the interest on the potential industrial use of Ulva ohnoi ( Prabhu et al, 2019 ) and its applicability or its products in aquaculture is recent ( Norambuena et al, 2015 ; Fernández-Díaz et al, 2017 ; Martínez-Antequera et al, 2021 ). U. ohnoi is widely distributed and easily grown, with fast growth rates even in recirculating fish farming systems ( Oca et al, 2019 ; Kang et al, 2021 ). Several studies have described effects on the immune system after dietary inclusion of U. ohnoi ( Fumanal et al, 2020 ; Kang et al, 2021 ; Martínez-Antequera et al, 2021 ).…”

“…U. ohnoi is widely distributed and easily grown, with fast growth rates even in recirculating fish farming systems ( Oca et al, 2019 ; Kang et al, 2021 ). Several studies have described effects on the immune system after dietary inclusion of U. ohnoi ( Fumanal et al, 2020 ; Kang et al, 2021 ; Martínez-Antequera et al, 2021 ). In addition, presence of nutraceutical components such as the polysaccharide ulvan has been identified in U. ohnoi extracts ( Fernández-Díaz et al, 2017 ).…”