Intestinal Microbiota in Children with Anemia in Southern Peru through Next-Generation Sequencing Technology

Diaz-Rodriguez, Karla; Pacheco-Aranibar, Jani; Manrique-Sam, Cecilia; Ita-Balta, Yuma; Toia, Águeda Muñoz del Carpio; López-Casaperalta, Patricia; Chocano-Rosas, Teresa; Fernandez-F, Fernando; Salas, José Villanueva; Bernabe-Ortiz, Julio Cesar

doi:10.3390/children9111615

Cited by 9 publications

(13 citation statements)

References 44 publications

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“…A reduced nutritional intake is known to shift the gut microbiome. For example, iron deficiency results in a reduction of Bifidob acterium, [210][211][212] Bacteroides, 213 and Faecalibacterium 214 and causes a shift in SCFA 215 as well as siderophore-production, 213 while an increase of the Actinobacteria phylum [216][217][218] is reported. Vitamin A deficiency rather promotes Enterococcus in children with diarrhea, 219 while Bacteroides and Bifidobacterium are decreased.…”

Section: Inflammationmentioning

confidence: 99%

Nutrition in chronic inflammatory conditions: Bypassing the mucosal block for micronutrients

Roth‐Walter,

Berni Canani,

O'Mahony

et al. 2023

Allergy

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Nutritional Immunity is one of the most ancient innate immune responses, during which the body can restrict nutrients availability to pathogens and restricts their uptake by the gut mucosa (mucosal block). Though this can be a beneficial strategy during infection, it also is associated with non‐communicable diseases—where the pathogen is missing; leading to increased morbidity and mortality as micronutritional uptake and distribution in the body is hindered. Here, we discuss the acute immune response in respect to nutrients, the opposing nutritional demands of regulatory and inflammatory cells and particularly focus on some nutrients linked with inflammation such as iron, vitamins A, Bs, C, and other antioxidants. We propose that while the absorption of certain micronutrients is hindered during inflammation, the dietary lymph path remains available. As such, several clinical trials investigated the role of the lymphatic system during protein absorption, following a ketogenic diet and an increased intake of antioxidants, vitamins, and minerals, in reducing inflammation and ameliorating disease.

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Section: Inflammationmentioning

confidence: 99%

Nutrition in chronic inflammatory conditions: Bypassing the mucosal block for micronutrients

Roth‐Walter,

Berni Canani,

O'Mahony

et al. 2023

Allergy

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“…A falta de conhecimento também poderia justificar a baixa de adesão dos profissionais, uma vez que segundo Rodríguez;Gomez;Camacho (2018)…”

Section: Resultsunclassified

Assistência integral à saúde: desafios e vulnerabilidades da assistência

2023

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Esta obra constituiu-se a partir de um processo colaborativo entre professores, estudantes e pesquisadores que se destacaram e qualificaram as discussões neste espaço formativo. Resulta, também, de movimentos interinstitucionais e de ações de incentivo à pesquisa que congregam pesquisadores das mais diversas áreas do conhecimento e de diferentes Instituições de Educação Superior públicas e privadas de abrangência nacional e internacional. Tem como objetivo integrar ações interinstitucionais nacionais e internacionais com redes de pesquisa que tenham a finalidade de fomentar a formação continuada dos profissionais da educação, por meio da produção e socialização de conhecimentos das diversas áreas do Saberes. Agradecemos aos autores pelo empenho, disponibilidade e dedicação para o desenvolvimento e conclusão dessa obra. Esperamos também que esta obra sirva de instrumento didático-pedagógico para estudantes, professores dos diversos níveis de ensino em seus trabalhos e demais interessados pela temática.

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“…Bioinformatic analysis were carried out as described in the Section 2 Material and Methods of the paper [21]. Briefly, the paired-end reads were merged using FLASH v. 1.2.7, and quality filtering for the raw labels was performed according to the QIIME quality control process.…”

Section: Bioinformatic Analysesmentioning

confidence: 99%

Characterization of Pulmonary Bacteriobiota in Critically Ill Patients in Southern Peru through Next-Generation Sequencing Technology

Quispe-Medina,

Pacheco-Aranibar,

Mamani-Ruelas

et al. 2023

CIMB

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Sequence variation in the 16S gene is widely used to characterize diverse microbial communities. This was the first pilot study carried out in our region where the pulmonary microbiota of critically ill patients was investigated and analyzed, with the aim of finding a specific profile for these patients that can be used as a diagnostic marker. An study of critical patients mechanically ventilated for non-respiratory indications, in a polyvalent intensive care unit, was carried out; samplee were extracted by endotracheal aspiration and subsequently the microbiota was characterized through Next-Generation Sequencing Technology (NGS). The predominant phyla among the critically ill patients were Proteobacteria, Firmicutes and Bacteroidata. In the surviving patients group, the predominant phyla were Proteobacteria, Bacteroidata and Firmicutes, in the group of deceased patients thy were Firmicutes, Proteobacteria, and Bacteroidata. We found a decrease in commensal bacteria in deceased patients and a progressive increase in in-hospital germs.

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Intestinal Microbiota in Children with Anemia in Southern Peru through Next-Generation Sequencing Technology

Cited by 9 publications

References 44 publications

Nutrition in chronic inflammatory conditions: Bypassing the mucosal block for micronutrients

Nutrition in chronic inflammatory conditions: Bypassing the mucosal block for micronutrients

Assistência integral à saúde: desafios e vulnerabilidades da assistência

Characterization of Pulmonary Bacteriobiota in Critically Ill Patients in Southern Peru through Next-Generation Sequencing Technology

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