Intra-articular Injections in the Treatment of Symptoms from Ankle Arthritis: A Systematic Review

Vannabouathong, Christopher; Fabbro, Gina Del; Sales, Brendan; Smith, Christopher; Li, Chuan Silvia; Yardley, Darryl; Bhandari, Mohit; Petrisor, Bradley

doi:10.1177/1071100718779375

Cited by 53 publications

(51 citation statements)

References 32 publications

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“…Corticosteroids Corticosteroids (CS) have been widely used as non-surgical treatment for OA in clinical practice, yet very few studies have been done to prove its efficacy in foot and ankle OA [72]. The use of IA corticosteroids for ankle OA is limited to two studies [73]. Sarkin studied the effects of IA injections in 100 patients with ankle OA and found significant evidence that patients with less severe OA benefit more from corticosteroid injections [74].…”

Section: Injection Substratesmentioning

confidence: 99%

Injection Techniques for Common Chronic Pain Conditions of the Foot: A Comprehensive Review

et al. 2020

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Purpose of Review: This is a comprehensive literature review of the available evidence and techniques of foot injections for chronic pain conditions. It briefly describes common foot chronic pain syndromes and then reviews available injection techniques for each of these syndromes, weighing the available evidence and comparing the available approaches. Recent Findings: Foot and ankle pain affects 20% of the population over 50 and significantly impairs mobility and ability to participate in activities of daily living (ADLs), as well as increases fall risk. It is commonly treated with costly surgery, at times with questionable efficacy. Injection therapy is challenging when the etiology is anatomical or compressive. Morton's neuroma is a budging of the interdigital nerve. Steroid, alcohol, and capsaicin injections Enhanced Digital Features To view enhanced digital features for this article go to https://doi.org/10.6084/ m9.figshare.11836971.

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Section: Injection Substratesmentioning

confidence: 99%

Injection Techniques for Common Chronic Pain Conditions of the Foot: A Comprehensive Review

et al. 2020

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“…22 HyA can be associated with corticosteroids and other procedure as well, such as joint lavage, to reduce synovitis and increase viscosupplementation. [21][22][23] The same author (Rodriguez-Merchan) confirmed the efficacy of IA injection of HyA associated with CS in two recent reviews. In one of them, he evidenced some short-time benefits of the use of HyA alone or in combination with joint lavage or corticosteroids in HA of the knee.…”

Section: Hyaluronic Acidmentioning

confidence: 88%

“…A single needle puncture of mice's knee joints was used to recreate the same bleeding condition in HA. HyA is proven to be the only infiltrative drug with sufficient evidence to be recommended in ankle arthritis, although future RCTs are needed to compare the four types of treatment 21. The second study of Ravanbod investigated the role of MSCs on cartilage restoration of the knee in 32 rabbits with HA.…”

mentioning

confidence: 99%

“…The second study of Ravanbod investigated the role of MSCs on cartilage restoration of the knee in 32 rabbits with HA. HyA can be associated with corticosteroids and other procedure as well, such as joint lavage, to reduce synovitis and increase viscosupplementation [21][22][23]. The cartilage status, which was evaluated by scanning electron microscopy, showed an improvement in less surface irregularities, less active chondrocytes and less apoptosis in the MSC group compared with the other groups.…”

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confidence: 99%

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Haemophilic arthropathy: A narrative review on the use of intra‐articular drugs for arthritis

et al. 2019

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Introduction: Intra-articular injections of various drugs are commonly used in patients with degenerative osteoarthritis and also in haemophilic patients. Haemophilic arthropathy is a particular type of secondary osteoarthritis (OA), but the degeneration of strong synovial, cartilaginous and subchondral constituents is provoked by the direct action of iron and blood in the joint.Aim of the study: The aim of this study is to review the literature regarding the use of various intra-articular drugs in joints affected by haemophilic arthropathy. Methods: We reviewed the data from the literature; the search was performed on three medical electronic databases (PubMed, Cochrane Library and Scopus Web of Science) by three authors (B. E., A. M. and V. N.) from 3 December 2018 till 15 December 2018. The search string was as follows: (hyaluronic acid OR viscosupplementation OR platelet-rich plasma OR corticosteroid OR mesenchymal stem cells) AND (haemophilia OR haemophilic arthropathy OR haemophilic arthritis).Results: Once the research was performed, a total of 300 articles were identified. 47 selected articles were analysed by the reviewers, and the eligibility of the study inclusion was assessed independently. Twelve papers were included based on clear fulfilment of the inclusion criteria. Thirty-five articles were excluded for the following reasons: no full text or accessible data for 14 of them, 15 involved surgery or rehabilitation therapy as the primary topic and 6 were systematic reviews (the main topics were beyond the haemophilic arthropathy). Conclusion:Although the degree of scientific evidence of the publications on intraarticular injections of various drugs (hyaluronic acid, corticosteriods, PRP and MSCs) in haemophilia is very low, it seems that intra-articular injections of hyaluronic acid can relieve joint pain for months and can be repeated every 6-12 months, which is why they can be recommended. Corticosteroid injections seem to relieve joint pain for a few weeks, but their routine use is not recommended in haemophilia. The efficacy of PRP and MSCs in haemophilic arthropathy is pending confirmation, which is why they are not currently recommended. K E Y W O R D Sarthritis, arthropathy, drugs, haemophilia

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“…As evidências sobre as injeções de corticosteroide para osteoartrite do tornozelo são limitadas a quatro séries de casos, totalizando 298 indivíduos, com repostas sintomáticas positivas para uso de triancinolona e betametasona, com reduções parciais das médias na escala analógica visual (EAV) de dor em 35% dos pacientes. 51 As evidências sobre viscossuplementação com ácido hialurônico (AH) estão presentes em 19 estudos, 11 destes sendo séries de casos totalizando $ 400 pacientes. Respostas sintomáticas positivas baseadas em escores de dor e mobilidade, EVA e SF-36 ocorreram em $ 68% dos pacientes estudados.…”

Section: Injeções Intra-articularesunclassified

Osteoartrite do tornozelo

Godoy‐Santos

Fonseca

Giordano

et al. 2020

Rev Bras Ortop (Sao Paulo)

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ResumoA osteoartrite (OA) é caracterizada por uma degradação crônica, progressiva e irreversível da superfície articular, associada a inflamação articular. A principal etiologia da OA do tornozelo é pós-traumática e sua prevalência é maior entre os jovens e obesos. Apesar dos avanços no tratamento das fraturas ao redor do tornozelo, o risco geral de desenvolver OA pós-traumática do tornozelo após 20 anos do trauma é de quase 40%; especialmente nas fraturas bimaleolares de Weber tipo B e C e fraturas envolvendo a borda tibial posterior. Nas fraturas do tálus, essa prevalência se aproxima de 100%, dependendo da gravidade da lesão e do tempo de seguimento. Nesse cenário, é fundamental a compreensão atual das vias de sinalização moleculares envolvidas na senescência e apoptose dos condrócitos. O tratamento da OA do tornozelo é estagiado e guiado pelos sistemas de classificação, condições locais e do paciente. Os principais problemas são a limitada capacidade de regeneração da cartilagem articular, o baixo suprimento de sangue e a escassez de células-tronco progenitoras.A presente atualização resume evidências científicas básicas recentes da OA pós-traumática do tornozelo, com foco principal nas alterações metabólicas da sinóvia, da cartilagem e do líquido sinovial. Epidemiologia, fisiopatologia, implicações clínicas, e opções de tratamento são também discutidas.

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Intra-articular Injections in the Treatment of Symptoms from Ankle Arthritis: A Systematic Review

Abstract: Level III, systematic review.

Cited by 53 publications

References 32 publications

Injection Techniques for Common Chronic Pain Conditions of the Foot: A Comprehensive Review

Injection Techniques for Common Chronic Pain Conditions of the Foot: A Comprehensive Review

Haemophilic arthropathy: A narrative review on the use of intra‐articular drugs for arthritis

Osteoartrite do tornozelo

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