Intra-familial Transmission of Helicobacter pylori Infection in Children of Households with Multiple Generations in Vietnam

Nguyen, Van Bang; Nguyễn, Gia Khánh; Phung, Dac Cam; Okrainec, Karen; Raymond, Josette; Dupond, Christophe; Kremp, O.; Kalach, Nicolas; Vidal-Trécan, G.

doi:10.1007/s10654-006-9016-y

Cited by 32 publications

(30 citation statements)

References 39 publications

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“…H. pylori seroprevalence was 52.1% in adults and 42.8% in children ≤18 years old. Our findings are comparable to those reported in other community-based studies in Vietnam [10][11][12][13][14][15]. In one community-based study carried out in Kinh majority ethnic, using the same serological test, Hoang et al found an overall seroprevalence of H. pylori of 58.2% with 47.3% in children [10].…”

Section: Discussionsupporting

confidence: 88%

“…Vietnam is also home to 54 ethnic groups with different cultures, of which 75% to 80% are living in rural or remote areas [8,9]. High rates of H. pylori infection were reported in both hospital-based and community-based studies from Vietnam [10][11][12][13]. Different risk factors for H. pylori infection have been identified in the Kinh ethnic majority [10][11][12] and among ethnic minorities [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

“…High rates of H. pylori infection were reported in both hospital-based and community-based studies from Vietnam [10][11][12][13]. Different risk factors for H. pylori infection have been identified in the Kinh ethnic majority [10][11][12] and among ethnic minorities [13][14][15]. As the socioeconomic level and the lifestyle vary considerably among ethnic groups in the country, the prevalence of H. pylori infection and particularly the risk factors for this infection differed in previous studies [10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

“…Different risk factors for H. pylori infection have been identified in the Kinh ethnic majority [10][11][12] and among ethnic minorities [13][14][15]. As the socioeconomic level and the lifestyle vary considerably among ethnic groups in the country, the prevalence of H. pylori infection and particularly the risk factors for this infection differed in previous studies [10][11][12][13][14][15]. According to the General Statistics Office of the Government of Vietnam 2009 [9], the Muong is the thirst largest ethnic group in Vietnam after the majority Kinh and Tay ethnic groups with an estimated more than one million people.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and Risk Factors of Helicobacter pylori Infection in Muong Children in Vietnam

Nguyen¹

2017

Ann Clin Lab Res

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Aim: H. pylori infection is predominantly acquired in early childhood. The aim of the present study was to determine the prevalence of H. pylori infection and to identify factors associated with the infection in Muong children living in Vietnam. Materials and methods:In a cross-sectional study 918 asymptomatic individuals of all generations living together in the same home were selected from 219 households, based on cluster sampling of residential location in Hoabinh Province, Vietnam. H. pylori infection status was determined by serology test on samples obtained at each visit. A questionnaire was filled out at the start of the study. H. pylori serology data were analyzed using χ 2 test and logistic regression models. Results Conclusion:The first community-based study in Muong population showed familial clustering in multi-generation population and supported the hypothesis of person-toperson transmission in H. pylori infection

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence and Risk Factors of Helicobacter pylori Infection in Muong Children in Vietnam

Nguyen¹

2017

Ann Clin Lab Res

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“…For example, crowded living conditions and high population density are associated with increased rates of microbial transmission, and similar conditions would be expected to increase intrafamilial spread. H. pylori acquisition, for example, is enhanced under such conditions (Cervantes et al 2010, Ford et al 2007, Goodman et al 2005, Goodman & Correa 2000, Nguyen et al 2006.…”

Section: Vertical and Horizontal Transmissionmentioning

confidence: 99%

The Human Microbiota as a Marker for Migrations of Individuals and Populations

Domínguez-Bello

Blaser

2011

Annu. Rev. Anthropol.

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In this review, we discuss evidence that the microbes that constitute the human microbiota coevolved with humans and maintain complex community and host interactions. Because these microbes are mostly vertically transmitted, they have evolved within each human group and provide a view of human ancestry. In particular, we discuss using Helicobacter pylori as a marker of ancestry and migrations. Other organisms with more mixed vertical and horizontal transmission are not suitable to trace migrations with any fidelity. Human mixing affects microbial phylogeographic signals, and lifestyles impact the human microbiome population structure. A decade after the human genome was sequenced, we are gaining insights into the population structure of the human microbiome. We also examine whether, rather than focus on the genetics of single microbial populations, a wider approach to the study of human ancestry based on the human microbiome is now possible.

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Prevalence and Risk Factors of Helicobacter pylori Infection in Elderly Patients With Upper Gastrointestinal Symptoms in Vietnam

Ho,

Quach

2024

JGH Open

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Background and AimHelicobacter pylori infection is a major cause of peptic ulcer disease and gastric cancer. Limited data exist on H. pylori prevalence and risk factors of infection among elderly individuals in Vietnam. This study aimed to determine the prevalence and associated risk factors of H. pylori infection in elderly Vietnamese patients with upper gastrointestinal symptoms.MethodsA cross‐sectional study was conducted on patients aged ≥ 60 years with upper gastrointestinal symptoms who underwent endoscopy. The exclusion criteria included recent antibiotic or proton pump inhibitor use, prior H. pylori eradication, or upper gastrointestinal surgery. Data on demographics, hygiene, diet, and history were collected through structured questionnaires. H. pylori was diagnosed by a rapid urease test. Logistic regression was used to analyze risk factors.ResultsOf 406 participants (mean age 65.4 ± 4.5 years, male‐to‐female ratio 1:2), H. pylori prevalence was 55.6%. The risk factors for H. pylori infection included infrequent tooth brushing (OR 18.14, 95% CI 3.94–83.55), overweight/obesity (OR 5.82, 95% CI 3.44–9.88), spicy food consumption (OR 5.18, 95% CI 2.74–9.79), a family history of upper gastrointestinal symptoms (OR 3.15, 95% CI 1.84–5.39), and cat ownership (OR 2.01, 95% CI 1.10–3.68). The vegetarian diet was protective (OR 0.04, 95% CI 0.01–0.18).ConclusionsH. pylori prevalence in elderly Vietnamese is high, with risk factors including poor hygiene, obesity, spicy food, family history, and cat ownership. A vegetarian diet may be protective.

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Intra-familial Transmission of Helicobacter pylori Infection in Children of Households with Multiple Generations in Vietnam

Cited by 32 publications

References 39 publications

Prevalence and Risk Factors of Helicobacter pylori Infection in Muong Children in Vietnam

Prevalence and Risk Factors of Helicobacter pylori Infection in Muong Children in Vietnam

The Human Microbiota as a Marker for Migrations of Individuals and Populations

Prevalence and Risk Factors of Helicobacter pylori Infection in Elderly Patients With Upper Gastrointestinal Symptoms in Vietnam

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