Intracerebral haemorrhage in a dog with steroid‐responsive meningitis arteritis

Abstract

A one‐year and six‐month‐old female neutered Boxer dog was presented with a four‐day history of pyrexia, lethargy and neck pain. An intracerebral haemorrhage and a mediastinal mass were identified. Cerebrospinal fluid analysis revealed severe neutrophilic pleocytosis, and steroid‐responsive meningitis arteritis (SRMA) was suspected. A significant improvement was observed with immunosuppressive steroid therapy and subsequent imaging revealed a reduction in size of the intracerebral haemorrhage and disappearance of the mediastinal mass. SRMA is a systemic disease with potential involvement of multiple organs. Intracerebral haemorrhage can occur secondary to SRMA and can have a successful outcome.

Presumptive Spontaneous Hemothorax Associated to Thymic Involution in a Dog with Steroid Responsive Meningitis-Arteritis (SRMA)

“…17,18 Therefore, systemic vasculitis and perivasculitis can develop and potentially interfere with the patient's hemostatic response. [17][18][19] In fact, increased fibrinolysis has been described in the cerebrospinal fluid of dogs with SRMA. 14 Although more studies are needed to know the aetiopathological mechanism of SRMA, there is increasing evidence that this disorder affects systemic vascular beds, organs outside of nervous system, such us arteries of the heart, cranial mediastinum, and cervical spinal meninges.…”