Intracorporeal Use of the Hemostatic Agent QuickClot in a Coagulopathic Patient with Combined Thoracoabdominal Penetrating Trauma

A case Series Describing Thermal Injury Resulting From Zeolite Use for Hemorrhage Control in Combat Operations

“…3 In addition, there is one case study reporting successful use in a civilian coagulopathic patient with thoracoabdominal trauma. 7 Concern, however, has been raised over the exothermic process created with the zeolite granules during the adsorption of free fluid. Mild 10,11 to severe 8,9,12 exothermic reactions, with corresponding tissue damage, have been reported in animal studies.…”

“…In fact, there is growing interest in the use of these products in the civilian prehospital setting, emergency departments, and operating rooms throughout North America. 7 However, previous studies have raised concern about possible thermal injury to surrounding viable tissue due to an exothermic reaction created with zeolite use. 8,9 This case series is the first human description of thermal injury associated with zeolite use for hemorrhage control in current combat operations.…”

Adjuncts for Tissue stasis

“…112 After sustaining multiple gunshot wounds the patient was noted to have a large posterior chest wound. Unsuccessful attempts at surgical control of hemorrhage were followed by massive transfusion and coagulopathy that resulted in diffuse bleeding.…”

The 2004 Fitts Lecture: Current Perspective on Combat Casualty Care

“…These products include new tourniquets and new guidelines for tourniquet usage, improved hemostatic products-from powders to dressings to better gauze and advanced hemostatic dressings-IV hemostasis with fresh whole blood, and recombinant coagulation factor VIIa (Kauvar DS, et al, unpublished material, 2005). [22][23][24][25][26] Rather than approach the problem of hemorrhage in a linear fashion, the DoD has deployed multiple products at multiple levels to improve hemorrhage control across the board. Wide use of these products and, perhaps more importantly, even wider appreciation of the importance of early hemorrhage control has likely resulted in a decrease in the killed in action rate.…”