Intracranial Collision Metastases of Small-Cell Lung Cancer and Malignant Melanoma

Palka, Kevin; Lebow, Richard L.; Weaver, Kyle D.; Kressin, Megan K.

doi:10.1200/jco.2007.14.5540

Cited by 10 publications

(5 citation statements)

References 11 publications

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“…Most of them describe cases with collision tumors consisting of malignant astrocytoma (including glioblastoma) and meningioma3,6,7,9,10). There are also reports of collision tumors consisting of two different cerebral metastases2,8). In almost all of these cases, the collision tumor consists of at least one malignant entity, but in our case, the collision tumor consists of two benign entities.…”

Section: Discussionmentioning

confidence: 66%

Collision Tumor Composed of Meningioma and Cavernoma

Weigel

Schrey

et al. 2017

J Korean Neurosurg Soc

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A true collision tumor is a rare entity composed of two histologically distinct neoplasms coinciding in the same organ. This paper reports a unique case of cerebral collision tumor consisting of two benign components. On the first hand, meningioma which is usually a benign lesion arising from the meningothelial cell in the arachnoidal membrane. On the other, cerebral cavernoma which is a well-circumscribed, benign vascular hamartoma within the brain. To our knowledge, there is no previously documented case of cerebral collision tumor consisting of two benign components. A 56-year-old Caucasian male suffered in 2002 from an atypical meningioma WHO II° located in the left lateral ventricle. Three years after the tumor extirpation, the patient suffered from a hematoma in the fourth ventricle due to a recurrently haemorrhaged cavernoma. In 2008, a recurrence of the tumor in the left lateral ventricle was discovered. Additionally, another tumor located in the quadrigeminal lamina was detected. After surgical resection of the tumor in the left lateral ventricle, the pathological examination confirmed the diagnosis of a collision tumor consisting of components of a meningioma WHO II° and a cavernoma. Postoperatively, no adjuvant treatment was needed and no tumor recurrence is discovered up to the present. A possible explanation for the collision of those two different tumors may be migration of tumor cells mediated by the cerebrospinal fluid. After 5-years of follow-up, there is no sign of any tumor recurrence; therefore, surgical tumor removal without adjuvant therapy seems to be the treatment of choice.

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Section: Discussionmentioning

confidence: 66%

Collision Tumor Composed of Meningioma and Cavernoma

Weigel

Schrey

et al. 2017

J Korean Neurosurg Soc

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“…These tumors should however be differentiated from composed/mixed/combined neoplasms, actually consisting of a tumor with various differentiation (i.e., sarcomatoid carcinoma and/or carcinosarcoma) but deriving from a unique neoplastic clone (metaplastic theory) [6]. In the lit- Lung Adenocarcinoma/metastatic breast carcinoma erature, the term collision tumor in the lungs has been erroneously adopted to describe primary carcinomas with various differentiations [9]. Although collision tumors may represent an incidental curiosity or an academic exercise, sometimes they may pose important clinical dilemmas.…”

Section: Discussionmentioning

confidence: 99%

Primary pulmonary cancer colliding with metastatic breast carcinoma: Hitherto unreported cases of cancer-to-cancer metastasis focusing on clinical implications

et al. 2011

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“…Collision tumors may be located anywhere in the body. A collision tumor of the breast has been described ( 8 ), as has an intracranial collision metastasis ( 9 ). Similar to the present case, a collision tumor of a papillary thyroid carcinoma and a laryngeal squamous cell carcinoma has been previously reported ( 7 ).…”

Section: Discussionmentioning

confidence: 99%

Papillary thyroid carcinoma and laryngeal squamous cell carcinoma manifesting as a collision tumor of the neck: A case report

et al. 2013

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A 55-year-old male presented with a rapidly expanding mass on the right side of the neck and progressive hoarseness. An electronic laryngoscopy and a computed tomography scan were performed, and the patient was subsequently diagnosed with tumors of the larynx and the thyroid gland. An en bloc near-total thyroidectomy combined with a total laryngectomy was performed. The final pathological analysis revealed a collision tumor that was derived from a laryngeal squamous cell carcinoma and a papillary thyroid carcinoma. Collision tumors of the head and neck are rare. The therapy for a collision tumor should consist of a combination of the treatments that are normally used for each focus.

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Intracranial Collision Metastases of Small-Cell Lung Cancer and Malignant Melanoma

Cited by 10 publications

References 11 publications

Collision Tumor Composed of Meningioma and Cavernoma

Collision Tumor Composed of Meningioma and Cavernoma

Primary pulmonary cancer colliding with metastatic breast carcinoma: Hitherto unreported cases of cancer-to-cancer metastasis focusing on clinical implications

Papillary thyroid carcinoma and laryngeal squamous cell carcinoma manifesting as a collision tumor of the neck: A case report

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