Intracranial Extra-axial Chondroma: A Case Report

Abstract

Intracranial chondroma is a rare benign neoplasm that occurs most often at the skull base. In extremely rare instances, it arises from the dura mater of the convexity or from the falx cerebri. The tumor cells are thought to originate from meningeal fibroblasts, perivascular mesenchymal tissue, or ectopic chondrocytes. Because the clinical presentation of such cases is nonspecific and because neuroimaging findings are not pathognomonic, intracranial chondromas mimic other intracranial tumors. Herein, we report a chondroma originating from the dura mater in the frontal region. The patient had been followed-up radiologically for 3 years after a preliminary diagnosis of meningioma until the correct diagnosis of chondroma was established with postoperative histological examination.

Giant Dural Supratentorial Chondroma Generating the Question of How Large Can a Tumor Become without Revealing Itself

“…The publications regarding convexity chondromas are shown in Table 1 . 2 , 7-28 A given predominance of the left hemisphere can be seen. The frontoparietal region is the most common localization of the tumor.…”

“…Therefore, the final diagnosis was chondroma. Other tumors that have to be considered in the differential diagnosis are meningiomas, 2 hemangiopericytomas, gliomas and metastases. Immunohistochemistry is an important tool in establishing the diagnosis.…”

A young male presenting with swelling on the left lower anterior aspect of the neck

“… 1 Small bones of the hands and feet are most commonly involved, sometimes it may also occur in the ribs and pelvis, and rarely in the intracranial bones. 2 Enchondromas are rarely present in the spine, comprising 2% of all chondromas. 3 An enchondroma may occur as a single tumor or many tumors together.…”

“…The treatment of choice for chondroma is complete surgical excision. 2 Although recurrence of chondroma is rare, it can recur with incomplete removal. Nearly 10% of solitary chondromas undergo malignant transformation that requires radiation therapy.…”

Chondroma of the Cerebral Falx: Case Report of a Very Rare Intracranial Tumor

“…Chondroma is a benign cartilaginous tumor, usually arising from the small bones of hands and feet, but also been found on several sites of the body. 1,2 They are rarely diagnosed inside the cranial vault, and in that case more frequently related with the skull base. Nevertheless, there are few isolated cases reports of chondromas arising from the con-vexity dura, falx, choroid plexus, or intraparenchymal.…”