Intracranial fungal granuloma: analysis of 40 patients and review of the literature

Dubey, Arvind Kumar; Patwardhan, Ravish V.; Sampth, Sammana; Santosh, Vani; Kolluri, Sastry; Nanda, Anil

doi:10.1016/j.surneu.2004.04.020

Cited by 152 publications

(160 citation statements)

References 23 publications

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“…Trichophyton, Microsporum and Epidermophyton have the ability to invade keratinized tissues, such as hair, skin or nails, of humans causing dermatophytosis including tinea corporis, tinea pedis and onychomycosis (Weitzman, Summerbell, 1995;Koroishi et al, 2008). Aspergillus flavus and A. parasiticus causes different clinical manifestations of human aspergillosis such as cutaneous aspergillosis, aspergillar otomycosis, aspergillar onychomycosis, invasive lung aspergillosis and aspergillar sinusitis (Dubey et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Origanum essential oils for inhibition of potentially pathogenic fungi

Souza

Lima

Guedes

et al. 2010

Braz. J. Pharm. Sci.

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Section: Introductionmentioning

confidence: 99%

Efficacy of Origanum essential oils for inhibition of potentially pathogenic fungi

Souza

Lima

Guedes

et al. 2010

Braz. J. Pharm. Sci.

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“…Dubey et al 5 have reported 40 cases of granulomatous mycotic brain lesions collected in 23 year-time span. In this series, the authors referenced only 3 cases (7 %) caused by C. neoformans.…”

Section: Discussionmentioning

confidence: 99%

Cerebellar cryptococcoma simulating metastatic neoplasm

Sillero-Filho

Souza²,

Vaitsman

et al. 2009

Arq. Neuro-Psiquiatr.

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Neurocryptococcosis is a common mycotic central nervous system infection caused by the neurotropic fungus Cryptococcus neoformans 1 . It is most frequently found as the pathological presentation of cryptococcal meningoencephalitis 1 . Other rare forms of central nervous system cryptococcal infections are their solid-granulomatous appearance and abscesses, both being commonly named neurocryptococcomas, because of the mass effect they cause in surrounding tissue and their "tumoral aspect", many times simulating a brain tumor. Alternatively, Nucci et al. 2 described the unique report of a pseudocystic form of neurocryptococcosis. These medical conditions were classically described in immunocompromised hosts, mainly in HIV/AIDS infected patients.However, more recently, such disease has also been found in HIV-negative, immunocompetent individuals 1,3,4 . HIV-negative patients who were diagnosed with neurocryptococcoma had frequently other predisposing conditions to immunologic dysfunction such as sarcoidosis, diabetes, recent use of glucocorticoid or other immunossupresive therapy, as pointed by Gologorsky et al. 4 . CASEA 46 year-old male patient was admitted to the emergency room complaining of about two months of occipital headache, associated with nausea and vomiting in the last two days. Altered mental status had already been detected by his family within the last twelve hours before admittance. On neurological examination there was mild confusion and Glasgow coma scale score was 13. The patient was submitted to a contrast enhanced head computed tomography (CT) scan, which revealed a left cerebellar hemispheric tumor-like lesion with ring-like contrast enhancement, measuring about 2.8 cm on its major diameter. The lesion presented with surrounding edema, which caused fourth [A, B and C]. Complete resection of the lesion by a suboccipital craniectomy is shown in Fig 1D.

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“…2,3 However, infection can occur in an immunocompetent human. 4 Similar to CNS Aspergillus infection, cases of granulomatous amoebic encephalitis (GAE) due to Acanthamoeba species (A. castellanii, A. polyphaga, A. culbertsoni, and probably other amoebas) have also been documented in chronically ill and debilitated or naturally or iatrogenically immunologically suppressed individuals with severe derangements of the host defenses. In cases of GAE, the route of invasion of amoebas into the CNS is hematogenous, probably from a primary focus in the lower respiratory tract or the skin.…”

Section: Introductionmentioning

confidence: 99%

Rare Case of Meningoencephalitis Due to Aspergillus and Acanthamoeba Coinfection

2015

Human Parasitic Diseases

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Aspergillus and Acanthamoeba cause central nervous system (CNS) infection mostly in immunocompromised hosts, disseminating via the hematogenous route from a primary focus in the respiratory tract. We are presenting a case of an immunocompetent patient diagnosed with Aspergillus and Acanthamoeba coinfection of the CNS, a rare finding. A positive cerebrospinal fluid (CSF) galactomannan antigen test confirmed the presence of Aspergillus, and direct visualization in CSF sample and culture confirmed the presence of Acanthamoeba.

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Intracranial fungal granuloma: analysis of 40 patients and review of the literature

Cited by 152 publications

References 23 publications

Efficacy of Origanum essential oils for inhibition of potentially pathogenic fungi

Efficacy of Origanum essential oils for inhibition of potentially pathogenic fungi

Cerebellar cryptococcoma simulating metastatic neoplasm

Rare Case of Meningoencephalitis Due to Aspergillus and Acanthamoeba Coinfection

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