Intracranial ganglioneuromas in children

Arseni, C; Horvath, Lenke; Carp, N; Ciurea, V

doi:10.1007/bf01405460

Cited by 16 publications

(7 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The association of ganglioneuroma with pheochromocytoma also has been reported in the human adrenal gland [2 11, while ganglioneuromas without coincident pheochromocytomas have been found at other sites in man [1,16] and animals [4,10,15,20]. These include the adrenal glands [4,7,15,16] …”

Section: Discussionmentioning

confidence: 93%

“…The Schwann's cells were surrounded by a basement membrane and formed long cytoplasmic extensions around the axons. Almost all ganglioneuromas were associated with neoplastic pheochromocytes which usually were located at the edge of the tumors.Tumors of neurogenic origin (neuroblastoma, ganglioneuroblastoma, ganglioneuroma) are the most common solid abdominal neoplasms found in children [1,2,5,12,16,22,23]. Forty percent of them arise in the adrenal medulla [6].…”

mentioning

confidence: 99%

“…Tumors of neurogenic origin (neuroblastoma, ganglioneuroblastoma, ganglioneuroma) are the most common solid abdominal neoplasms found in children [1,2,5,12,16,22,23]. Forty percent of them arise in the adrenal medulla [6].…”

mentioning

confidence: 99%

See 2 more Smart Citations

Ganglioneuromas in the Adrenal Medulla of F344 Rats

1980

View full text Add to dashboard Cite

Abstract. Of 60,048 aging F344 rats, 28 had ganglioneuromas of the adrenal gland. The rats were between 58 and 122 weeks old; 25 of them between 93 and 122 weeks when the tumors were found. The neoplasms were composed of large or small typical ganglion cells with a large pale nucleus and a prominent, often eccentric, nucleolus. The ganglion cells usually were distributed throughout the medullary tumor and surrounded by various numbers of supporting cells, including Schwann's cell types, and capsular or satellite cells. Often there was no clear-cut border between ganglion cells and neoplastic pheochromocytes. Electron microscopy of re-embedded tissues showed neurosecretory granules and cytoplasmic areas with an extensive rough endoplasmic reticulum (Nissl substance) in the ganglion cells and axons. The Schwann's cells were surrounded by a basement membrane and formed long cytoplasmic extensions around the axons. Almost all ganglioneuromas were associated with neoplastic pheochromocytes which usually were located at the edge of the tumors.Tumors of neurogenic origin (neuroblastoma, ganglioneuroblastoma, ganglioneuroma) are the most common solid abdominal neoplasms found in children [1,2,5,12,16,22,23]. Forty percent of them arise in the adrenal medulla [6]. We do not presently have a model system for studying the pathogenesis of these tumors in animals. None of the known cancer-inducing agents has produced a significant number of tumors of this type in the abdominal cavity of experimental animals, nor do they often occur spontaneously in untreated animals [7][8][9][10]19,20].Histological data on more than 60,000 F344 rats had accumulated from past bioassays. From these, we reviewed the morphology of 28 ganglioneuromas diagnosed histologically from adrenal gland tumors of F344 rats. The tumor samples were retrieved from the bioassay experiments conducted in the NCI Carcinogenesis Testing Program from 1972 to 1979 [13], and included material from chemically treated and untreated (control) rats. Materials and MethodsThe rats had been obtained when 6 weeks old from commercial suppliers and studied for 2 years [9]. Necropsies were done on all animals found dead and on those that were moribund 614

show abstract

Section: Discussionmentioning

confidence: 93%

mentioning

confidence: 99%

See 1 more Smart Citation

Ganglioneuromas in the Adrenal Medulla of F344 Rats

1980

View full text Add to dashboard Cite

show abstract

“…1,[3][4][5]8,9,11,12) Only one case of ganglioneuroma has arisen from the trigeminal nerve, 1) and one case of cranial``true'' ganglioneuroma. 5) We recently treated a patient with ganglioneuroma arising from the maxillary nerve and extending to the middle cranial fossa, and describe the perioperative course, neuroimaging find- …”

Section: Introductionmentioning

confidence: 99%

Ganglioneuroma Originating From the Trigeminal Nerve in the Middle Cranial Fossa

Nakaguchi

Murakami

Matsuno

et al. 2012

Neurol. Med. Chir.(Tokyo)

View full text Add to dashboard Cite

A 55-year-old man present with a case of ganglioneuroma manifesting as sudden onset of severe headache. T 1 -weighted magnetic resonance imaging demonstrated a heterogeneously enhanced mass (3 × 3 × 2.5 cm) in the left middle cranial fossa compressing the left cavernous sinus. The tumor was totally removed through a frontozygomatic approach. The histological diagnosis was ganglioneuroma originating from the second division of the trigeminal nerve in the middle cranial fossa. Ganglioneuroma can occur wherever ganglion cells exist, but ganglioneuroma originating from the trigeminal nerve is rare, with only two cases reported.

show abstract

“…gion, [2][3][4][5][6][7][8] with only three cases has been reported arising from trigeminal nerve. [2][3][4] The current paper presents a 49-year-old male patient with a ganglioneuroma arising from right trigeminal ganglion and extending to the middle-posterior cranial fossa.…”

mentioning

confidence: 99%

Trigeminal Ganglioneuroma in the Middle-posterior Cranial Fossa: a Case Report△

Wang

Lou

et al. 2017

Chinese Medical Sciences Journal

View full text Add to dashboard Cite

CASE DESCRIPTIONA 49-year-old male patient with no previous comorbidities presented to our hospital with a main complaint of discontinuous dizziness for one month. The dizziness was paroxysmal onset without obvious cause. General physical examination demonstrated right facial muscle atrophic, with no other abnormality. All the neurologic examination was negative.Computed tomography (CT) scan of the brain discovered a slight hypodensity mass (4.2cm×5.2cm) in the right middle-posterior cranial fossa with internal high-density dots in the tumor (Fig. 1A). The tumor deformed the ethmoid bone, destroyed the greater wing of the sphenoid bone and the petrous apex area, and extended to the carvernous sinus and posterior cranial fossa. The pons was compressed. CT value of the spotty high-density was about 350HU, consistent with localized intratumoral calcification and hemorrhage. CT images in bone window demonstrated absorption and thinning of the sphenoid and ethmoid bone without destruction (Fig. 1B). The brain magnetic resonance imaging (MRI) showed a 4.1cm×5.4cm×4cmwell-circumscribed extra-axial mass in the parasellar and cerebellopontine angle region of right middle-posterior cranial fossa (Fig. 2). The right fifth-sixth cranial nerve was displaced by the mass. The lesion demonstrated heterogeneous isointensity or slight hypointensity on T1-weighted image (T1WI), heterogeneous hyper-to slight hypointensity on T2-weighted image (T2WI) (Fig. 2A). It compressed G

show abstract

Intracranial ganglioneuromas in children

Cited by 16 publications

References 1 publication

Ganglioneuromas in the Adrenal Medulla of F344 Rats

Ganglioneuromas in the Adrenal Medulla of F344 Rats

Ganglioneuroma Originating From the Trigeminal Nerve in the Middle Cranial Fossa

Trigeminal Ganglioneuroma in the Middle-posterior Cranial Fossa: a Case Report△

Contact Info

Product

Resources

About