Intracranial Subdural Empyemas in the Era of Computed Tomography: A Review of 699 Cases

Abstract

Intracranial subdural empyema, which is a neurosurgical emergency, is rapidly fatal if not recognized early and managed promptly. Early surgical drainage, simultaneous eradication of the primary source of sepsis, and intravenous administration of high doses of appropriate antibiotic agents represent the mainstays of treatment.

Fulminant Subdural Empyema Treated With a Wide Decompressive Craniectomy and Continuous Irrigation. Case Report.

“…2) Delay in diagnosis and surgical intervention might result in a fatal outcome. 7) The most important factors correlated with favorable outcomes are early aggressive removal of the source of infection, drainage of pus, and appropriate antibiotic administration. 1,3) We describe a case of fulminate subdural empyema treated with decompressive craniectomy.…”

Microbiology and management of brain abscess in children

“…Since the advent of CT and MRI scanning, the case fatality rate has fallen by 90%. Arteriograms and ventriculograms are invasive techniques that are infrequently indicated (13).…”

Neuro-Intensive Care of Patients with Acute CNS Infections

“…For infections likely caused by aerobic Gram-negative bacilli, empiric therapy with cefepime or meropenem is indicated pending finalized culture and sensitivity results. With appropriate management, mortality rates are 10% in patients with good mental status at presentation, but mortality increases to 50% in patients that present later in infection with significant changes in mental status or semi-comatose state [95,96]. Thus, early and emergent intervention is vital to improve outcomes in patients with subdural empyema.…”