2020
DOI: 10.21037/atm-20-1121a
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Intracytoplasmic sperm injection outcomes in patients with orgasmic dysfunction and anejaculation by percutaneous epididymal sperm aspiration (PESA)

Abstract: Background: Orgasmic dysfunction and anejaculation are two uncommon yet powerful factors of male infertility. The treatment of orgasmic dysfunction and anejaculation is especially important for men who desire paternity, who otherwise would have to undergo surgical sperm retrieval for use with intracytoplasmic sperm injection (ICSI). We evaluated the reproductive outcomes of percutaneous epididymal sperm aspiration (PESA) for ICSI in a cohort of infertile patients who had presented with orgasmic dysfunction and… Show more

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Cited by 5 publications
(7 citation statements)
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“…These men may suffer from high levels of oxidative stress, impaired mitochondrial function, DNA damage and impairment of the reproductive axis; ejaculatory disorders may also exist (Abbasihormozi et al, 2019). Treatment of diabetes may improve fertility outcomes and potentially be cost‐effective (Fang et al, 2020; Mazzilli et al, 2020). Notwithstanding that investigating and treating infertile diabetic male will also improve their general health and morbidity (Tharakan et al, 2019).…”
Section: Discussionmentioning
confidence: 99%
“…These men may suffer from high levels of oxidative stress, impaired mitochondrial function, DNA damage and impairment of the reproductive axis; ejaculatory disorders may also exist (Abbasihormozi et al, 2019). Treatment of diabetes may improve fertility outcomes and potentially be cost‐effective (Fang et al, 2020; Mazzilli et al, 2020). Notwithstanding that investigating and treating infertile diabetic male will also improve their general health and morbidity (Tharakan et al, 2019).…”
Section: Discussionmentioning
confidence: 99%
“…From the perspective of andrology, the primary treatment purpose of CBAVD is to solve the problem with the goal of enabling the conception of genetic offspring, and CBAVD is often discovered and diagnosed because of long-term male infertility. With the development of sperm extraction technology and ART, CBAVD patients can achieve fertility with the aforementioned two technologies (Elhanbly et al, 2015;Fang et al, 2020;Jixiang et al, 2021). For CBAVD patients, the first step of ART methods, such as intracytoplasmic sperm injection (ICSI), is the procedure for obtaining sperm.…”
Section: Treatment and Art Outcomesmentioning
confidence: 99%
“…If infertility is an issue, several approaches can be employed: (1) Assisted ejaculation by penile vibratory stimulation (PVS) is an option for sperm retrieval[ 136 ] because it is noninvasive and inexpensive[ 137 ]. However, DM patients frequently fail to obtain sperms by this method because it requires intact lumbosacral pathways[ 136 , 137 ]; (2) In cases in whom PVS fails, electroejaculation (EEJ) may be effective to retrieve spermatozoa[ 99 , 138 ]; and (3) If these procedures fail, surgical sperm retrieval can be tried through VD aspiration[ 139 ], percutaneous epididymal sperm aspiration (PESA)[ 140 ], or testicular sperm extraction (TESA)[ 141 ]. Using spermatozoa obtained by any of these procedures and utilizing intracytoplasmic sperm injection (ICSI), one can attain clinical pregnancy and live birth rates in DM-related AE.…”
Section: Diabetes-related Ejaculatory Dysfunctionsmentioning
confidence: 99%
“…Using spermatozoa obtained by any of these procedures and utilizing intracytoplasmic sperm injection (ICSI), one can attain clinical pregnancy and live birth rates in DM-related AE. However, the fertilization rate and high-quality embryo rate in diabetic PE patients are lower than in non-diabetic PE patients[ 140 ].…”
Section: Diabetes-related Ejaculatory Dysfunctionsmentioning
confidence: 99%