Intraductal papillary mucinous tumors of the pancreas: spectrum of CT and MR findings with pathologic correlation

Abstract

The reports of intraductal papillary mucinous tumors (IPMT) of the pancreas are increasingly more frequent in the literature. The diagnosis by means of cross-sectional imaging of these tumors is not easy, especially in the early stages, when they can mimic an inflammatory disease of the pancreas. Prompt identification of the disease is nevertheless extremely important, especially in the case of tumors originating from the collateral branches, since its recognition can modify the management of the patient, in some cases obviating recourse to surgery.

Imaging features of intraductal papillary mucinous neoplasms of the pancreas in multi-detector row computed tomography

“…The data in this study also complied with this rule. However, compared with the published series from Europe, Japan, and the USA [9,[29][30][31][32] , the main duct IPMN had a lower rate of malignancy (1 of 3) in the present study, whereas the combined-type IPMNs demonstrated malignancy in more cases (10 of 12) on pathology. The sensitivity, specificity, and accuracy of MDCT in characterizing the malignancy of IPMNs were 100%, 87.5% and 95%, respectively.…”

“…According to the site and extent of involvement, IPMNs are classified into three subtypes: main duct type, branch duct type, and combined-type (mixed type) with both main and branch duct lesions [2,7,8] . Although an IPMN is a rare tumor, the increasingly common use of imaging techniques has contributed to the identification of an increasing number of the lesions, even in entirely asymptomatic cases [9][10][11][12][13] . According to the International Guidelines for management of IPMN [2] , magnetic resonance imaging (MRI) along with magnetic resonance cholangiopancreatography (MRCP) is referred to as the best imaging modality to outline the gross appearance of IPMN.…”

Contrast-enhanced ultrasound of the pancreas

“…the identification of vascularized inclusions (Figure 4), and for the differential diagnosis between MCA and a pseudocyst [17,46] . IPMNs are cystic tumors of the pancreas recently reported with increasing frequency [6,38,41,47,48] . They are macroscopically characterized by having an intraductal origin and growth [49] , with the production of dense mucin that fills the main pancreatic duct (the ductectatic mucin-hypersecreting variant) or with endoluminal papillary proliferation (the papillary-villous variant).…”

Clinicopathological subclassification of biliary cystic tumors: Report of 4 cases with a review of the literature

“…These entities can be regarded as the biliary counterparts of pancreatic entities (7)(8)(9). The biologic similarities between the biliary and pancreatic ductal systems have attracted attention because both organs are derived from the ventral endoderm of the foregut (10).…”