Intraindividual comparison of 1,470 nm diode laser versus carbon dioxide laser for tonsillotomy: A prospective, randomized, double blind, controlled feasibility trial

Havel, Miriam; Sroka, Ronald; Englert, Erno; Stelter, Klaus; Leunig, Andreas; Betz, Christian

doi:10.1002/lsm.22053

Cited by 23 publications

(20 citation statements)

References 23 publications

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“…PTH may have been reported as primary (generally defined as occurring within 24 hours of surgery), secondary (generally defined as occurring more than 24 hours postoperatively), or at an undefined or unspecified time. 8–108 Seventy-three studies contributed data to the meta-analysis (66 RCTs, 19,20,23,25,27,29,33,34,36,38–41,43,44,46,47,49,50,52–59,62–64,67,71,72,74–79,81–84,88–92,95,101–105,108–122 6 nonrandomized trials, 24,35,37,45,48,94 and 1 prospective cohort study 70 ). The resulting subset of studies included the following tonsillectomy techniques: cold dissection, electrocautery, coblation, harmonic scalpel, laser, molecular resonance, thermal welding, and microdebrider.…”

Section: Resultsmentioning

confidence: 99%

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Postoperative Bleeding and Associated Utilization following Tonsillectomy in Children: A Systematic Review and Meta‐analysis

Francis

Fonnesbeck

Sathe

et al. 2017

Otolaryngol.--head neck surg.

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Objective To assess post-tonsillectomy hemorrhage (PTH), associated non-operative readmissions/revisits, and reoperations in children. Data Sources MEDLINE, EMBASE, and the Cochrane Library. Review Methods Two investigators independently screened studies against predetermined criteria and extracted key data. Investigators independently assessed study risk of bias and the strength of the evidence of the body of literature. We calculated unadjusted pooled estimates of PTH frequency and also conducted a Bayesian meta-analysis to estimate frequency of primary and secondary PTH and PTH-associated reoperation and revisits/readmissions by partial and total tonsillectomy and surgical approach. Results In meta-analysis, the frequency of primary and secondary PTH associated with total and partial tonsillectomy was below 4% for any technique and with overlapping confidence bounds. Pooled frequencies of PTH were also below 5% overall (4.2% for total tonsillectomy; 1.5% for partial tonsillectomy) in comparative studies. Fewer PTH occurred with tonsillectomy for obstructive sleep-disordered breathing than throat infection. In meta-analysis, frequency of PTH-associated non-operative revisits/readmission or reoperation ranged from 0.2% to 5.7% for total tonsillectomy and from 0.1% to 3.7% for partial tonsillectomy. At least four deaths were reported in case series including 1,778,342 children. Conclusions PTH occurred in roughly 4% of tonsillectomies in studies included in this review. Though studies typically did not report bleeding severity or amount, relatively few episodes of PTH necessitated reoperation for hemostasis. Nonetheless, tonsillectomy is not without risk of harm. Frequency of PTH across techniques was similar; thus we cannot conclude that a given technique is superior.

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Section: Resultsmentioning

confidence: 99%

“…No PTH was associated with laser approaches, but few, small studies (n=54 children total) assessed this modality. 29,99,100 …”

Section: Resultsmentioning

confidence: 99%

Postoperative Bleeding and Associated Utilization following Tonsillectomy in Children: A Systematic Review and Meta‐analysis

Francis

Fonnesbeck

Sathe

et al. 2017

Otolaryngol.--head neck surg.

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“…Several other studies have also shown that lowpower laser irradiation has a positive therapeutic effect in a number of clinical situations (Havel et al 2012)e.g., pain relief (Fonseca et al 2012), wound healing (Kirkby et al 2012), and sports medicine (Wheeland 2012). This effect occurs through a mechanism involving acceleration of cell division, increased enzyme activity, collagen production (Calatrava et al 1997), regulation of mitochondrial processes (Karu 2008;Eells et al 2004;Prusa et al 2012), increased expression of certain proteins (Ozog et al 2012), induced synthesis of cell cycle regulatory proteins (Ocanã-Quero et al 1998a) and increase ATP production (Kirkby et al 2012;Karu 2010;Gavish et al 2004).…”

Section: Introductionmentioning

confidence: 95%

Enhancement of monoclonal antibody production in CHO cells by exposure to He–Ne laser radiation

et al. 2013

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This study tested the effectiveness of laser biostimulation in small-scale cultures in vitro. We investigated the response of recombinant CHO cells, which are used for the production of monoclonal antibody, to low level laser radiation. The cells were irradiated using a 632.8 nm He-Ne laser in a continuous wave mode at different energy doses. We incubated the irradiated cells in small batch cultures and assessed their proliferation and productivity at various time intervals. Compared to untreated cells, the irradiated cells showed a significant increase in antibody production. Moreover, the results showed that laser irradiation did not affect viability and slightly enhanced proliferation rate.

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“…Fest steht aber inzwischen, dass die Teilentfernung bei der kindlichen Tonsillenhyperplasie mit obstruktivem Schlafapnoesyndrom (OSAS) oder Rhonchopathie eine sofortige Verbesserung bringt [29,30,31,32] und dass anamnestische Tonsillitiden in keinem Alter (sechs Monate bis 72 Jahre) als Kontraindikation einer Teilresektion der Tonsillen gesehen werden.…”

Section: Operative Therapie -Tonsillotomieunclassified

Wieviel Tonsillektomie darf es noch sein?

Stelter¹,

Kisser²

2016

HNO Nachrichten

Self Cite

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Die Tonsillitis gehört zweifelsohne zu jenen Erkrankungen, mit denen der HNO-Arzt besonders häu g konfrontiert ist. Die Therapie wird jedoch sehr unterschiedlich gehandhabt und insbesondere hinsichtlich des operativen Vorgehens herrscht Uneinigkeit. Die im August 2015 erschienene neue Leitlinie zur Behandlung der Tonsillitis beschäftigt sich ausführlich mit der operativen Therapie und gibt interessante neue Empfehlungen.

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Intraindividual comparison of 1,470 nm diode laser versus carbon dioxide laser for tonsillotomy: A prospective, randomized, double blind, controlled feasibility trial

Cited by 23 publications

References 23 publications

Postoperative Bleeding and Associated Utilization following Tonsillectomy in Children: A Systematic Review and Meta‐analysis

Postoperative Bleeding and Associated Utilization following Tonsillectomy in Children: A Systematic Review and Meta‐analysis

Enhancement of monoclonal antibody production in CHO cells by exposure to He–Ne laser radiation

Wieviel Tonsillektomie darf es noch sein?

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