Intralesional Triamcinolone Acetonide (TA) Versus Incision and Curettage (I &amp; C) for Medium and Large Size Chalazia

Singhania, Renu; Sharma, Nidhi; Vashisht, Shashi; Dewan, Taru

doi:10.3126/nepjoph.v10i1.21661

Cited by 9 publications

(12 citation statements)

References 13 publications

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“…In most of the studies when the success rate was high, available TMA was 6-8 mg with more than 1 injection and low success rate when available TMA was 2-4mg. 6,8,13,14 In our study group A cases received 8mg TMA and group B 2mg TMA hence there is statistically significant difference (P=0.05). This support the assumption of higher concentration of TMA has better results compare to lower concentration TMA.…”

Section: Discussionmentioning

confidence: 54%

“…Reported complications of depot steroid injection in chalazion treatment are hypo pigmentation/de pigmentation of lid skin, 6,7,24 yellow white deposits in the lid skin, 9 subconjunctival eye lid fat atrophy, 24 second injection, 13,14 corneal perforation with traumatic cataract by injection needle, 25 micro embolism of retinal and choriodal vasculature leading to infarction, 26 steroid induced glaucoma, 7,27 and subcapsular cataract. 7 The commulative complications in our study was 10% (6/60).…”

Section: On Comparing the Outcomementioning

confidence: 99%

“…12 Advantages of intralesional TMA injections are simple outpatient department (OPD) procedure, no anesthesia injection requirement, minimal bleeding, no post procedure scarring, multiple chalazion can be treated at a time , easy to treat chalazion near punctual area and usefull in children and anxietic patients. 2,3 Many studies have been done on the efficacy and complications of TMA injection with various concentration and number of injections, 6,7,13 comparing the response with size of the chalazion, 14 duration of the chalazion, 5,6 gender and between different age group. 3 We have failed to find any literature on comparing the two concentration of triamcinolone (TMA) 40mg/ml and 10mg/ml in treatment of chalazion in journals, Medline and Pubmed on line search.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of intralesional injection of triamcinolone - 40 mg/ml and Triamcinolone -10 mg/ml in treatment of chalazion

Naik¹,

Vasu²

2021

IJOOO

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A prospective, randomised and comparative study to compare the efficacy and complications of triamcinolone acetonide (TMA)40mg/ml with TMA 10mg/ml in treatment of Chalazion.Sixty chalazion patients were randomly grouped into two groups. Group A patients received single intralesional injection of 0.2ml TMA 40mg/ml and group B 0.2ml of TMA 10mg/ml. The outcome and complications are evaluated at the end of 6 weeks. There were 60 chalazion from 58 patients, two patients with bilateral chalazion. There were 28 chalazion in group A and 32 chalazion in group B.Over all cure rate was 68.3% (41/60) and comparable to earlier study (P=0.70). The success rate of 78.6%(22/28) in group A is significantly more than the success rate of 56.3%(18/32) in group B (P=0.05). The cumulative complications are marginally more in group A 14.3 % (4/28) (7.2% with raised intraocular pressure (IOP) of>15 mmHg and 7.2% with cosmetically blemish yellow white deposit in skin) compare to 6.3% (2/32) in group B (cosmetically blemish yellow white deposit in skin) (P=0.41). Single dose of intralesional injection of higher concentration of TMA 40mg/ml is more effective than TMA 10mg/ml. However vision threatening complication of raised IOP and Aesthetical dissatisfaction due to yellow white deposit in the lid skin are the disadvantages. Glaucoma comprehensive eye examination and repeated counseling sessions in cosmetically anxious young female patients to be kept in mind.

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Section: Discussionmentioning

confidence: 54%

Section: On Comparing the Outcomementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Comparison of intralesional injection of triamcinolone - 40 mg/ml and Triamcinolone -10 mg/ml in treatment of chalazion

Naik¹,

Vasu²

2021

IJOOO

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“…Singhania et al, studied the same success rate of two groups between medium and large sized chalazion and found that Intralesional TA was as effective as Incision and curettage for both medium and large sized chalazion. 15 While Khurana et al concluded that Incision and curettage was better choice in case of larger chalazion. 16 In our study, recurrence was found as 3.3% in Incision and curettage group and 10% in TA group.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Peri-lesional Triamcinolone Acetonide versus Incision and Curettage in the Treatment of Primary Chalazion

Imtiaz¹,

Jabran²,

Anam³

et al. 2021

pak J Ophthalmol

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Purpose: To compare the results of peri-lesional Triamcinolone Acetonide (TA) with incision and curettage in the treatment of primary chalazia. Study Design: Quasi experimental study. Place and Duration of Study: Eye department of District Head Quarter/Teaching Hospital, Gujranwala, from June 2018 to May 2019. Methods: One hundred and twenty patients with primary chalazion, either gender and age between 10–30 years, were enrolled in this study. They were equally divided into two groups. In group A, incision and curettage was done. In group B, perilesional TA (40 mg/ml) was given. Followup was done at 5th day, 14th day, 1 month and 3 months. Lesion resolution or recurrence and complications were recorded. IOP monitoring was also carried out at each followup. Results: Mean age was 18.0 ± 2.14 years with range of 10–30 years. There were 45.0% females and 55.0% males. No statistically significant difference was found in age, gender and complication rates between the two groups. Complete resolution was seen in 95.0% in group A and 88.3% cases in group B. The difference between the two groups was not statistically significant regarding small and medium sized chalazia. In case of large chalazia, 23 out of 24 patients in group A and 19 out of 23 patients in group B showed complete resolution and the difference in success rate of two groups was statistically significant (p = 0.014). Conclusion: Incision and curettage and perilesional TA injection are equally effective in treating small and medium primary chalazia. While for large chalazia, Incision and curettage offered superior results. Key words: Chalazion, incision and curettage, triamcinolone Acetonide,

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“…A 2016 meta-analysis compared steroid injection with I&C and concluded that the surgical intervention was more effective after one procedure (60% vs 78%) with a decrease in relative efficacy if taking into account a second attempt (73% vs 87%); there were no differences in complication rates between the two procedures 4. Singhania et al noted that the resolution of medium to large size chalazia (chalazia diagnosis was confirmed by biopsy) was comparable between one steroid injection (90% for medium and 74% for large) and I&C (92% for medium and 91% for large) taking an average of 2–3 weeks to resolve; the reason for the better results in the steroid group may be attributed to removal of material within the lesion for biopsy before steroid injection 19. In a study of 536 patients, I&C resulted in satisfactory outcome in 91% of cases though chalazia recurred in 6% of cases 20.…”

Section: Discussionmentioning

confidence: 99%

<p>Low level light therapy for the treatment of recalcitrant chalazia: a sample case summary</p>

Stonecipher¹,

Potvin²

2019

OPTH

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PurposeTo evaluate the effects of low-level light therapy (LLLT) on the resolution of recalcitrant chalazia.Patients and MethodsThis was a single-site retrospective chart review of patients with chalazia, all of whom were unresponsive to previous pharmaceutical therapy or surgical intervention, who received a 15 min LLLT treatment in conjunction with a standard pharmaceutical regimen. A second treatment was applied 24 hrs to as late as 2 months if there was no evidence of progression of resolution in appearance.ResultsA total of 26 eyes of 22 patients with relevant history and treatment were reviewed, all with a history of prior pharmaceutical treatment for their chalazia. After a single 15 min LLLT treatment, followed by a standard pharmaceutical regimen, 46% of eyes (12/26) showed resolution of their chalazia. Resolution was noted from 3 days to one-month post-treatment. With a second treatment, the chalazia resolved in 92% of eyes (24/26). Only two eyes of the 26 (8%) required incision and curettage after LLLT treatment.ConclusionThe use of LLLT for the treatment of recalcitrant chalazia appears to be beneficial in patients who have failed topical and/or systemic therapy, significantly reducing the likelihood of requiring surgical intervention.

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Intralesional Triamcinolone Acetonide (TA) Versus Incision and Curettage (I & C) for Medium and Large Size Chalazia

Cited by 9 publications

References 13 publications

Comparison of intralesional injection of triamcinolone - 40 mg/ml and Triamcinolone -10 mg/ml in treatment of chalazion

Comparison of intralesional injection of triamcinolone - 40 mg/ml and Triamcinolone -10 mg/ml in treatment of chalazion

Comparison of Peri-lesional Triamcinolone Acetonide versus Incision and Curettage in the Treatment of Primary Chalazion

<p>Low level light therapy for the treatment of recalcitrant chalazia: a sample case summary</p>

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