Intralymphatic Histiocytosis Associated with Osteoarthritis: A Case Report

Koo, Taehan; Kang, Hyunil; Kim, Min-Soo; Jue, Mihn‐Sook

doi:10.5021/ad.2022.34.3.225

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…[ 3 ] Numerous cases of intralymphatic histiocytosis have been reported in association with various inflammatory and neoplastic diseases, including rheumatoid arthritis, reactions to metal joint implants, Merkel cell carcinoma, breast cancer, and colon cancer. [ 4 , 5 ] Allergies, chronic inflammation, and lymphangiectasis may be potential causes. Lymphatic drainage obstruction is typically caused by congenital abnormal vessels or damage acquired to the lymphatic vessels from infection, trauma, surgery, or radiation.…”

Section: Discussionmentioning

confidence: 99%

Intralymphatic histiocytosis of the upper eyelid in a patient of Korean descent: A case report

Ha,

Kim,

Lee

2023

Medicine

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Rationale: Diagnosing intralymphatic histiocytosis can be challenging due to its rarity. We present a case of intralymphatic histiocytosis in the upper eyelid of a Korean patient. We treated the condition by surgical debulking and intralesional triamcinolone injection. Patient concerns: A 59-year-old man was referred to our clinic with a 7-year history of unilateral swelling in the right upper eyelid. He had previously been treated with long-term oral steroids and immunosuppressants, but his eyelid swelling persisted. Unilaterally non-pitting erythematous edema was localized on the right upper eyelid without any itching or pain. His best corrected visual acuity at presentation was 20/20 for both eyes. Enhanced orbital computerized tomography revealed edematous soft tissue thickening in the right upper eyelid. In the laboratory testing, the erythrocyte sedimentation rate showed an increase of 19, and the antinuclear antibody titer was positive with a homogeneous pattern. Diagnoses: We diagnosed the patient with intralymphatic histiocytosis based on the histopathological findings. Intervention: We attempted surgical debulking and biopsy on the right upper eyelid due to the persistent symptoms and the absence of a definitive diagnosis. Outcomes: The patient has demonstrated significant improvement after receiving an intralesional triamcinolone injection in the right upper eyelid following the surgery and is currently under follow-up with no signs of recurrence. Lesson: Ophthalmologists should consider intralymphatic histiocytosis in cases of persistent eyelid swelling that do not respond to treatment, even in Asian patients. Surgical debulking and intralesional triamcinolone injections may be beneficial for improvement.

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Section: Discussionmentioning

confidence: 99%

Intralymphatic histiocytosis of the upper eyelid in a patient of Korean descent: A case report

Ha,

Kim,

Lee

2023

Medicine

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“…Indeed, two patients in their study who had no evident systemic process occurring at the time of skin biopsy were eventually diagnosed with IH. Regarding associations with systemic disease, rheumatoid arthritis is the most common disease association [76][77][78][79][80][81][82][83][84][85], but IH has also been reported in osteoarthritis [86,87], Merkel cell carcinoma [81], mastectomy sites [81,88], joint replacements and metal implants [81,84,[88][89][90], breast implants [91], melanoma [81], Klippel-Trenaunay syndrome [81], Crohn's disease [76], cellulitis [92], and genital swelling and necrosis [84,93].…”

Section: Clinical Presentationmentioning

confidence: 99%

Cutaneous Intravascular Hematolymphoid Entities: A Review

Marshall,

Brumbaugh,

Holt

et al. 2024

Diagnostics

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Intravascular lymphomas are rare disease conditions that exhibit neoplastic lymphoid cells that are confined mainly to the lumens of small capillaries and medium-sized vessels. The majority of the intravascular lymphomas are of B-cell origin, but they can include NK/T-cell and CD30+ immunophenotypes. In the histologic differential diagnosis are benign proliferations such as intralymphatic histiocytosis and intravascular atypical CD30+ T-cell proliferation. In this review, we discuss the clinical, histopathologic, and molecular findings of intravascular B-cell lymphoma, intravascular NK/T-cell lymphoma, intralymphatic histiocytosis, and benign atypical intravascular CD30+ T-cell proliferation.

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