Intraneural Perineurioma of the Radial Nerve in a Child

Medial Elbow Mass in an 18-year-old Woman

“…[6,12,13]. In one study, a predilection for the upper extremity was reported [6]; however, research has found a nearly equal incidence of upper and lower extremity involvement [12][13][14]. The definitive cause of these tumors is still being investigated [5,10].…”

“…Patients typically present with a painless mononeuropathy, which includes progressive weakness throughout affected muscles, classically sparing sensation [6,11,16]. In the largest study to date, 29 patients presented with a chief complaint of weakness or atrophy and only three with numbness or pain.…”

“…Cortes et al [6], based on a 9-year-old patient with good results postoperatively, recommended early surgical resection with reconstruction in the young patient. Improved recovery of function in children and adolescents compared with adults, regardless of method of repair, duration, or location of injury, has been reported [3,6,[21][22][23][24].…”

“…Improved recovery of function in children and adolescents compared with adults, regardless of method of repair, duration, or location of injury, has been reported [3,6,[21][22][23][24]. However, contradicting evidence also has shown disappointing outcomes in adolescents who were treated with surgical resection [6,18,19].…”

Intraneural perineurioma of the radial nerve visualized by 3.0 Tesla MRI

“…3,7,9,12 The literature has classified two distinctive types based on localization: intraneural and extraneural (soft tissue). [2][3][4][5] Intraneural perineurioma is composed of perineurial cells that surround the nerve as a diffusion barrier between blood and the nerve. 14,21,25,26 The tumor cells stain positively for vimentin, epithelial membrane antigen (EMA), and glucose transporter protein 1.…”