Intraocular Lens Complications Requiring Removal or Exchange

Carlson, Alan N.; Stewart, William C.; Tso, Patrick C.

doi:10.1016/s0039-6257(97)00140-9

Cited by 87 publications

(40 citation statements)

References 206 publications

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“…In fact, tilt and decentration of the implanted IOLs could limit or even cancel out the theoretical advantages of aspheric IOLs. [23][24][25][26][27] In summary, the results of the current study show that the EnVista IOL studied provides a good optical performance, however, the optical quality results for this IOL were worse than for the aberration-correcting IOL. Hence, it seems that it would be interesting to consider other designs for this new IOL with other degrees of SA in order to optimize its results in a wider spectrum of patients.…”

Section: Discussionmentioning

confidence: 57%

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In vitro optical performance of a new aberration-free intraocular lens

Madrid-Costa

Ruiz-Alcocer

Ferrer-Blasco

et al. 2014

Eye

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Purpose To assess the optical performance of the new EnVista intraocular lens (IOL). Materials and methods Four aspheric IOLs were evaluated; the new EnVista is one amoung them. This IOL, similarly to the Z-Flex HB and the Bi-Flex 1.8 667AB ones, has a neutral aspheric design, whereas the fourth IOL under test (AcrySof IQ IOL SN60WF) presents a negative spherical aberration (SA). The IOL's aberration patterns were measured in vitro, by setting them up on an optical bench. From these aberration-pattern data, the modulation transfer function (MTF), the average modulation values, and the points spread function (PSF) were calculated. Furthermore, in order to assess the potential optical quality that these IOLs would yield once they are implanted, an average cornealaberration pattern was juxtaposed to the in-vitro profiles and the same parameters were calculated again. Results For the IOL-only scenario (ie, without including the corneal factor), it was the EnVista IOL, which is aberration-free that showed the higher MTF, PSF values. This was followed by the other two aberrationfree IOL models. However, when the effect of an average corneal pattern was also taken into consideration, the AcrySof IQ IOL SN60WF always outperformed the other neutral-asphericity IOLs. Conclusions The in-vitro optical performance of the EnVista IOL was good, but it decreases substantially in a whole-eye scenario, when the wavefront profile of an average cornea is added. Other designs with different degrees of SA should be considered for this IOL in order to surpass these results.

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Section: Discussionmentioning

confidence: 57%

“…One of the most important factors is the required accuracy of the centration of the lens. [18][19][20][21][22][23][24] Decentration of an IOL can lead to other common complication: tilt. In fact, tilt and decentration of the implanted IOLs could limit or even cancel out the theoretical advantages of aspheric IOLs.…”

Section: Discussionmentioning

confidence: 99%

In vitro optical performance of a new aberration-free intraocular lens

Madrid-Costa

Ruiz-Alcocer

Ferrer-Blasco

et al. 2014

Eye

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“…9 However, many of these medical devices fail to produce long term therapeutic effect raising serious concerns over the efficiency of these implants. [10][11][12][13][14][15][16][17] For example, the chemotherapeutic doxorubicin delivering millirods has been reported to lose efficacy 8 days post subcutaneous implantation. 8 .…”

Section: Introductionmentioning

confidence: 99%

Species and Density of Implant Surface Chemistry Affect the Extent of Foreign Body Reactions

et al. 2008

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Implant-associated fibrotic capsule formation presents a major challenge for the development of long term drug release microspheres and implantable sensors. Since material properties have been shown to affect in vitro cellular responses and also to influence short term in vivo tissue responses, we have thus assumed that the type and density of surface chemical groups would affect the degree of tissue responses to microsphere implants. To test this hypothesis, polypropylene particles with different surface densities of -OH and -COOH groups, along with the polypropylene control (-CH 2 groups) were utilized. The influence of functional groups and their surface densities on tissue reactions were analyzed using a mice subcutaneous implantation model. Our comparative studies included determination and correlation of the extents of fibrotic capsule formation, cell infiltration into the particles and recruitment of CD11b+ inflammatory cells for all of the substrates employed. We have observed major differences among microspheres coated with different surface functionalities. Surfaces with -OH surface groups trigger the strongest responses while -COOH rich surfaces prompt the least tissue reactions. However, variation of the surface density of either functional group has a relatively minor influence on the extent of fibrotic tissue reactions. The present results show that surface functionality can be used as a powerful tool to alter implant-associated fibrotic reactions and, potentially, to improve the efficacy and function of drug delivery microspheres, implantable sensors and tissue engineering scaffolds.

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“…Dislocation of a posterior chamber intraocular lens (IOL) typically occurs after decentralization, followed by migration to the vitreous cavity through a rupture area of the equatorial portion of the posterior capsule (1)(2) or through posterior capsulotomy with neodymium: YAG laser (3)(4) . A new type of IOL dislocation has been recently described, involving total IOL luxation within an intact capsular bag.…”

Section: Introductionmentioning

confidence: 99%