Intraoperative Detection of a Bronchial Carcinoid With a Radiolabeled Somatostatin Analog

Diagnosis and treatment of lymph node metastases of a rectal carcinoid tumor using In111-octreotide-scintigraphy and intraoperative gamma probe detection

“…7,8 Using the probe for radioguided surgery, intraoperatively after administration of Indium111-octreotide, is more sensitive than using SRS or intraoperative palpation, therefore it allows a more radical surgery. [9][10][11][12][13] However, we have to point out that this procedure can be quite complicated since, the probe detects a relatively large amount of background due to nearby structures (mainly small bowel) which may retain the radioactive tracer. The problem can be partly solved with a careful study of visualization times of both the lesion and the intestine at the time of SRS diagnostics.…”

Primary hepatic carcinoid tumor in children

“…High-resolution CT scanning may locate unrecognized mass lesions in the chest, abdomen, and pelvis. Radiolabeled somatostatin analog scintigraphy may also identify previously hidden primary disease [18][19][20]. Finally, as carcinoid tumors frequently produce serotonin and the secretory granule product chromogranin A, serum levels of these products may remain elevated after resection in patients with unrecognized primary disease [21].…”

Radioguided surgery in neuroendocrine tumors. A review of the literature

“…33 It is of note that 111 In-pentetreotide plays an important role in the differential diagnosis of the hypersecretion of ACTH, distinguishing between pituitary adenomas and bronchial carcinoid tumors which secrete ACTH and, in the latter case, localizing the tumor responsible for ectopic secretion. 34 Several authors [35][36][37] have performed radioguided surgery after the administration of 111 In-pentetreotide. The procedure not only allows precise localization of the tumor but determines its total resection, and, in the case of residual lesion, completes the resection.…”