Intraoperative lymphatic mapping for early-stage melanoma of the head and neck

Bostick, Peter J.; Essner, Richard; Sarantou, Terry; Kelley, Mark C.; Glass, Edwin C.; Foshag, Leland J.; Stern, Stacey L.; Morton, Donald L.

doi:10.1016/s0002-9610(97)00150-5

Cited by 130 publications

(104 citation statements)

References 16 publications

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“…Second, most patients are now undergoing sentinel lymph node mapping without simultaneous complete regional lymphadenectomy. 5,7,13,15,16 Third, data have emerged that support the notion that more detailed analyses of sentinel lymph nodes will detect metastatic melanoma more often than routine analyses involving only hematoxylin-eosin staining of 1 or 2 sections. 7,10,17,18 The false-negative rate of sentinel lymph node mapping may be assessed by simultaneous ELND and comparison of the histological status of the sentinel lymph node with that of the remaining lymph nodes, as was originally described by Morton and colleagues.…”

Section: Commentmentioning

confidence: 99%

Outcome of Patients With Melanoma and Histologically Negative Sentinel Lymph Nodes

et al. 1999

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Section: Commentmentioning

confidence: 99%

Outcome of Patients With Melanoma and Histologically Negative Sentinel Lymph Nodes

et al. 1999

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“…15,30 While indirect lymphographyachieves accuracy up to 96% in melanoma of the head and neck its use in solid tumors of oral cavity requiring injections in the mucosa is restricted. [31][32][33][34] Generally dyes bear characteristics which dispose their very rapid migration through the lymphatic vessels, low invasive, easy reproducible and cheap but if used alone their productivity in SLN identifying is somehow limited to superficial tissue plains, in particular above the deep fascia on the trunk and the extremities and some allergic reaction on methylene blue, isosulfan blue and patent blue dyes reported in number of papers limited this technique to implement to all patients 3.…”

Section: 29mentioning

confidence: 99%

A Review of Techniques for Sentinel Lymph Node Mapping with Special Reference to the Head and Neck Region

Sun¹

2016

ICPJL

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Sentinel lymph node biopsy is an extensively explored diagnostic mean for reducing surgical risks while improving staging in different human malignancies. Several different techniques have been introduced to clinical use during last two decades. Methods as ink lymphography and lymphoscintigraphy have already established their position in sentinel nodes mapping. Novel approaches as CT, MRI-lymphography, contrast enhanced ultrasound and near-infrared fluorescence imaging possesses prominent potential advantages and demand further experience gaining. A review of the clinically utilized techniques is presented a special attention is drawn to their usefulness in the head and neck carcinomas work-up. Keywords

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“…Surgical biopsy of the sentinel node can replace extensive nodal dissections for staging nodal spread of melanoma. This is because the lymphatic spread of melanoma is orderly (3); the pathological status of the sentinel node is predictive of regional nodal involvement (4,5).…”

Section: Introductionmentioning

confidence: 99%

Sentinel Node Lymphoscintigraphy in Cutaneous Malignant Melanoma

2002

IJRA

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Until fairly recently radical nodal dissection was the only procedure available to identify and remove micrometastatic foci of nodal spread of malignant melanoma. A less invasive technique, biopsy of the first draining node, the sentinel node, has to been shown to accurately stage lymphatic spread.Identification of the sentinel node is possible using intradermal injection of a blue dye (such as isosulfan blue) and/or radionuclides (sentinel node lymphoscintigraphy). Sentinel node lymphoscintigraphy is advantageous because multiple nodal basins can be "simultaneously" imaged, and the sentinel node can be relatively easily localized with an intraoperative probe.Successful lymphoscintigraphy requires careful injection technique, rapid imaging, and in many cases acquisition of special views to localize nodes. In this article we will discuss the rationale for, the use of, and the methods for performing lymphoscintigraphy.

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Intraoperative lymphatic mapping for early-stage melanoma of the head and neck

Cited by 130 publications

References 16 publications

Outcome of Patients With Melanoma and Histologically Negative Sentinel Lymph Nodes

Outcome of Patients With Melanoma and Histologically Negative Sentinel Lymph Nodes

A Review of Techniques for Sentinel Lymph Node Mapping with Special Reference to the Head and Neck Region

Sentinel Node Lymphoscintigraphy in Cutaneous Malignant Melanoma

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