Intraoperative radiotherapy in the treatment of neuroblastoma: Report of a pilot study

Abstract

IORT usually can be completed in less than an hour. No IORT-associated complications were identified. IORT along with maximal tumor resection, external radiation, and chemotherapy enhances local tumor control.

Conformal proton radiation treatment for retroperitoneal neuroblastoma: Introduction of a novel technique

“…IORT is performed at the time of tumor resection, so it is a one-time procedure and thus is a single-fraction approach [3,19,20].…”

Intraoperative radiation therapy

“…Neuroblastoma (high-risk category) is a disease approached with an IORT component at UCSF [68]. The more recent up-date shows 23 patients treated (18 with gross total resection) with IORT doses in the range of 7-16 Gy and no EBRT added.…”

Clinical significance of intensive surgery with intraoperative radiation for advanced neuroblastoma: does it really make sense?

“…[3][4][5][6] However, the efficacy of intraoperative irradiation therapy (IORT) has been reported in advanced neuroblastoma. [7][8][9][10] To evaluate the clinical significance of extensive surgery with IORT in advanced neuroblastoma, our 17-year experience of IORT was reviewed in the current study.…”