Intraoral sebaceous carcinoma

Abuzeid, M. O.; Gangopadhyay, Kunal; Rayappa, C.; Antonios, J. I.

doi:10.1017/s0022215100134103

Cited by 27 publications

(9 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Intraoral sebaceous carcinoma was first reported by Damm et al in 1991 ( Table 1 , case 1) [ 4 ]. Since then, another 9 cases were reported in the literature ( Table 1 ) [ 4 – 6 , 8 – 14 ].…”

Section: Discussionmentioning

confidence: 99%

Intraoral Sebaceous Carcinoma: Case Report of a Rare Tumor Emphasizing the Histopathological Differential Diagnosis

Jawanda

Subramanyam

Grewal

et al. 2018

Case Reports in Dentistry

View full text Add to dashboard Cite

Background Sebaceous carcinoma (SC) is an uncommon cutaneous malignancy, usually occurring predominantly in the eyelids and only occasionally involving the oral cavity. Sebaceous carcinoma (SC) is a rare malignancy. Only 10 cases of sebaceous carcinoma of the oral cavity have been reported so far. Case Presentation A 40-year-old female presented with a mass on the left side of the middle third of the face. Radiographic findings were inconclusive. Resection of the mass was consistent with the diagnosis of primary sebaceous carcinoma. Conclusion Intraoral sebaceous carcinoma is uncommon. Due to its varied clinical appearance and presence of a diverse histopathologic appearance, the diagnosis is quite often confounding and elusive. Hence, it is imperative to familiarize oneself about various aspects of this rare tumor for earlier diagnosis, to improve the chances of patient's survival.

show abstract

Section: Discussionmentioning

confidence: 99%

Intraoral Sebaceous Carcinoma: Case Report of a Rare Tumor Emphasizing the Histopathological Differential Diagnosis

Jawanda

Subramanyam

Grewal

et al. 2018

Case Reports in Dentistry

View full text Add to dashboard Cite

show abstract

“…Reported follow-up for extraocular SC varies widely. With so few cases reported in the literature, it is difficult to assess the clinical behavior of extraocular 11 68/F Right cheek Regional lymph nodes 55/M Penis Inguinal lymph nodes 59/M Neck Regional lymph nodes, brain Hood et al 15 82/M Left nasal ala Regional lymph nodes, liver, lung, kidney Audisio et al 16 75/M Mammary fold Axillary lymph nodes, lung Jensen 17 62/F Scalp Regional lymph nodes, pleura, liver Dangou et al 33 65/M Maxillary angle Regional lymph nodes, clavicle Kawamoto et al 34 78/F Vulva Inguinal lymph nodes Magremanne et al 35 /M Nose Paramandibular region Antuna et al 18 53/M Scalp Cervical and lumbar spine, ribs, liver Abuzeid et al 36 11/F Buccal mucosa Regional lymph nodes Merono et al 37 45/M Axilla Subcutaneous tissue, axillary nodes Duman et al 38 65/F Forehead Hilar lung, liver, spleen, stomach Malhotra et al 39 60/F Angle of mouth Submandibular lymph node SC, although the previously reported cases of extraocular SC support the opinion that the biological behavior is similar to those occurring in the eyelid. 12 Thus, we would recommend long-term follow-up until more is known about extraocular SC behavior.…”

Section: Discussionmentioning

confidence: 99%

Should Extraocular Sebaceous Carcinoma Be Investigated Using Sentinel Node Biospy?

Sawyer

McGoldrick

Mackey

et al. 2009

Dermatologic Surgery

View full text Add to dashboard Cite

A 61-year-old man presented to his general practitioner (GP) with a 6-month history of an asymptomatic cutaneous lesion to the upper left side-wall of his nose. He was otherwise well and was taking no medication. Physical examination demonstrated a 5-Â 5-mm firm red cystic lesion. There was no evidence of regional metastases.The GP performed a biopsy using sharp ring curettage. Histology of the lesion demonstrated a sebaceous carcinoma (SC) (Figure 1). The subject was subsequently referred to our service.A literature review revealed the potential metastatic nature of extraocular SC. After discussion at our multidisciplinary team meeting, it was concluded that wide local excision with a 4-mm margin should be performed in combination with sentinel lymph node biopsy.The lymphoscintigraphy technique was used with technetium Tc-99m sulfur colloid and patent blue dye injected around the site of the original excision. Three level II (upper jugular group) nodes were localized using a radiation counter and direct visualization. These were excised. Lymphoscintigraphy images are shown in Figure 2.Wide local excision with a 4-mm margin was performed and the defect resurfaced with a fullthickness skin graft. Histology of the wide local excision showed no evidence of malignancy, and sentinel node biopsy from the left neck showed no evidence of metastatic disease. Three years after sentinel node biopsy, the subject had no evidence of any local or regional reoccurrence.We present the articles that have reported the metastatic nature of extraocular SC and report to the best of our knowledge the first extraocular SC sentinel node biopsy. We therefore advocate the benefit of sentinel node biopsy for these tumors.

show abstract

“…Sebaceous carcinoma is an uncommon adnexal neoplasm, usually localized to the head and neck (1–9). It occurs habitually in elderly patients and has no sex predominance (1–3).…”

Section: Discussionmentioning

confidence: 99%

“…Light microscopy with fat and PAS stain, searching for glycogen, lipid and mucin, are beneficial in differentiating SC from other tumors (1–10).…”

Section: Discussionmentioning

confidence: 99%

“…The histologic differential diagnosis of poorly differentiated SC includes cutaneous clear cell tumors, particularly epidermoid carcinoma with sebaceous differentiation, and, more rarely, clear cell acanthoma, clear cell hidradenoma, clear cell hidradenocarcinoma, tricholemmoma, pilar tumor, balloon cell melanoma, cutaneous clear cell carcinoma and metastatic renal cell carcinoma (1–10).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Undifferentiated Sebaceous Carcinoma: an Unusual Childhood Cancer

Mebazâa

Boussofara

Trabelsi

et al. 2007

Pediatric Dermatology

View full text Add to dashboard Cite

Sebaceous carcinoma is an aggressive, adnexal, rare malignant tumor that may arise in ocular or extra-ocular sites. Extraorbital sebaceous carcinoma is exceptional in childhood. We report a 12-year-old boy with an ocular sebaceous carcinoma who was first seen with an asymptomatic firm, cutaneous nodule on the right eyebrow. The tumor developed slowly within 1 year. Histologically, it was an undifferentiated sebaceous carcinoma. The patient had surgery with wide surgical margins. He was alive and free from disease at a follow-up of 34 months. Close follow-up of this tumor is recommended because of the risk of aggressive behavior.

show abstract

Intraoral sebaceous carcinoma

Abstract: Sebaceous carcinoma arising from the buccal mucosa is very rare. Only one such case has been reported in the English literature. We report a second case arising in an 11-year-old girl.

Cited by 27 publications

References 24 publications

Intraoral Sebaceous Carcinoma: Case Report of a Rare Tumor Emphasizing the Histopathological Differential Diagnosis

Intraoral Sebaceous Carcinoma: Case Report of a Rare Tumor Emphasizing the Histopathological Differential Diagnosis

Should Extraocular Sebaceous Carcinoma Be Investigated Using Sentinel Node Biospy?

Undifferentiated Sebaceous Carcinoma: an Unusual Childhood Cancer

Contact Info

Product

Resources

About